| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4682603 | B | Inhibition of human DNMT3B expressed in Escherichia coli Rosetta-gamiTM 2(DE3) pLysS competent cells using biotinylated 6-FAM double strand DNA comprising unique CpG site [3H]-SAM incubated for 1 hrs by fluorescence based assay | Homo sapiens | 14 | ALA4680123 | cell-based format | Scientific Literature | |
| 2. | ALA4682606 | B | Inhibition of human DNMT3B in human KG-1 cells expressing cmv-firefly luciferase assessed as increase in luminescence upto 10 uM incubated for 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 7 | ALA4680123 | cell-based format | Scientific Literature | |
| 3. | ALA4682608 | P | Chemical stability of compound in DNMT3A-c enzyme buffer assessed as half life at 1 mM by HPLC analysis | 7 | ALA4680123 | small-molecule physicochemical format | Scientific Literature | ||
| 4. | ALA4682610 | B | Inhibition of human DNMT3B in human KG-1 cells expressing cmv-firefly luciferase assessed as increase in luminescence at 5 uM incubated for 24 hrs by luciferase reporter gene assay relative to control | Homo sapiens | 3 | ALA4680123 | cell-based format | Scientific Literature |
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