# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4686182 | Binding | Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA | Homo sapiens | 24 | ALA4680229 | single protein format | Scientific Literature | |
2. | ALA4686183 | Binding | Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA | Homo sapiens | 15 | ALA4680229 | single protein format | Scientific Literature | |
3. | ALA4686184 | Binding | Selectivity index, ratio of IC50 for inhibition of human COX1 to IC50 for inhibition of human COX2 | Homo sapiens | 8 | ALA4680229 | assay format | Scientific Literature | |
4. | ALA4686185 | ADME | Cytotoxicity against rat C6 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Rattus norvegicus | 23 | ALA4680229 | cell-based format | Scientific Literature | |
5. | ALA4686186 | ADME | Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 23 | ALA4680229 | cell-based format | Scientific Literature |