# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4737341 | F | Antiviral activity against Ebola virus infected in human HuH7 cells assessed as reduction in viral infection pretreated for 2 hrs followed by viral infection and measured after 3 days by ZsGreen fluorescence assay | Ebolavirus | 17 | organism-based format | Scientific Literature | ||
2. | ALA4737342 | A | Cytotoxicity against human Huh-7 cells assessed as reduction in cell viability incubated for 3 days by cell-titer glo assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
3. | ALA4737343 | T | Selectivity index, ratio of CC50 for human Huh-7 cells to EC50 for Ebola virus infected in human HuH7 cells | 17 | cell-based format | Scientific Literature | |||
4. | ALA4737344 | B | Inhibition of Ebolavirus glycoprotein transfected in human Huh-7 cells cotransfected with HIV luciferase reporter vector expressing plasmid assessed as reduction in virus entry measured after 3 days by Bright-Glo luciferase assay | Ebolavirus | 2 | cell-based format | Scientific Literature | ||
5. | ALA4737345 | B | Inhibition of NPC1 in human HeLa cells assessed as increase in cholesterol accumulation in subcellular localization at 1 uM incubated for 24 hrs by filipin-staining based immunofluorescence assay | Homo sapiens | 2 | cell-based format | Scientific Literature |