| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4706222 | B | Inhibition of PDE8A1 (480 to 820 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 13 | assay format | Scientific Literature | ||
| 2. | ALA4706223 | B | Inhibition of PDE1B (146-506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 3. | ALA4706224 | B | Inhibition of PDE2A (518-919 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA4706225 | B | Inhibition of PDE3A (679-1087 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 5. | ALA4706226 | B | Inhibition of PDE4D2 (86-413 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 6. | ALA4706227 | B | Inhibition of PDE5A1 (535-860 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 7. | ALA4706228 | B | Inhibition of PDE7A1 (130-482 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 8. | ALA4706229 | B | Inhibition of PDE9A2 (181-506 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 9. | ALA4706230 | B | Inhibition of PDE10A (449-770 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 10. | ALA4706231 | B | Inhibition of PDE11A (588-911 residues) (unknown origin) expressed in Escherichia coli BL21 using [3H]-cAMP substrate incubated for 15 mins by liquid scintillation counting method | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA4706232 | B | Selectivity index, ratio of IC50 for inhibition of PDE1B (146-506 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA4706233 | B | Selectivity index, ratio of IC50 for inhibition of PDE2A (518-919 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA4706234 | B | Selectivity index, ratio of IC50 for inhibition of PDE3A (679-1087 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA4706235 | B | Selectivity index, ratio of IC50 for inhibition of PDE4D2 (86-413 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 15. | ALA4706236 | B | Selectivity index, ratio of IC50 for inhibition of PDE5A1 (535-860 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 16. | ALA4706237 | B | Selectivity index, ratio of IC50 for inhibition of PDE7A1 (130-482 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 17. | ALA4706238 | B | Selectivity index, ratio of IC50 for inhibition of PDE9A2 (181-506 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4706239 | B | Selectivity index, ratio of IC50 for inhibition of PDE10A (449-770 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4706240 | B | Selectivity index, ratio of IC50 for inhibition of PDE11A (588-911 residues) (unknown origin) to ratio of IC50 for PDE8A1 (480 to 820 residues) (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4706241 | A | Half life in Sprague-Dawley rat at 2.5 mg/kg, iv measured upto 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature |
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