| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4677187 | F | Antiproliferative activity against human NCI-H929 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay | Homo sapiens | 68 | ALA4673269 | cell-based format | Scientific Literature | |
| 2. | ALA4677188 | B | Inhibition of C-terminal TQ5WS-labelled QWAREIGAQLRRMADDLNAQY binding to human C-terminal Cy5-labelled Mcl-1 V321C/C286S mutant (171 to 321 residue) incubated for 2 hrs by fluorescence polarization analysis | Homo sapiens | 68 | ALA4673269 | assay format | Scientific Literature | |
| 3. | ALA4677189 | F | Induction of apoptosis in human AMO1 cells xenografted in CB-17 SCID mouse assessed as increase in cleaved PARP level at 12.5 mg/kg, iv administered as bolus dose measured after 16 hrs by immunodetection analysis relative to control | Homo sapiens | 26 | ALA4673269 | organism-based format | Scientific Literature |
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