# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4684613 | B | Inhibition of Trypanosoma brucei PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to control | Trypanosoma brucei | 15 | assay format | Scientific Literature | ||
2. | ALA4684614 | B | Inhibition of Leishmania major PTR1 using H2B as substrate preincubated for 10 mins followed by NADPH addition and measured up to 50 mins relative to control | Leishmania major | 15 | single protein format | Scientific Literature | ||
3. | ALA4684616 | F | Antitrypanosomal activity against bloodstream form of trypanosoma brucei brucei 427 assessed as reduction in parasitic growth after 72 hrs by resazurin staining based fluorescence assay | Trypanosoma brucei brucei | 13 | organism-based format | Scientific Literature | ||
4. | ALA4684619 | F | Antitrypanosomal activity against bloodstream form of trypanosoma brucei brucei 427 assessed as inhibition of parasitic growth at 1 uM after 72 hrs in presence of MTX by resazurin staining based fluorescence assay relative to control | Trypanosoma brucei brucei | 1 | organism-based format | Scientific Literature | ||
5. | ALA4684622 | F | Antitrypanosomal activity against bloodstream form of trypanosoma brucei brucei 427 assessed as inhibition of parasitic growth at 10 uM after 72 hrs by resazurin staining based fluorescence assay relative to control | Trypanosoma brucei brucei | 7 | organism-based format | Scientific Literature | ||
6. | ALA4684623 | F | Antitrypanosomal activity against bloodstream form of trypanosoma brucei brucei 427 assessed as inhibition of parasitic growth at 1 uM after 72 hrs by resazurin staining based fluorescence assay relative to control | Trypanosoma brucei brucei | 1 | organism-based format | Scientific Literature | ||
7. | ALA4684626 | F | Antitrypanosomal activity against bloodstream form of trypanosoma brucei brucei 427 assessed as potentiation index at 1 uM after 72 hrs in presence of MTX by resazurin staining based fluorescence assay | Trypanosoma brucei brucei | 1 | organism-based format | Scientific Literature | ||
8. | ALA4684629 | A | Cytotoxicity against human A549 cells assessed as reduction in cell viability by Cell Titer-Glo assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
9. | ALA4684630 | A | Cytotoxicity against human THP-1 cells assessed as reduction in cell viability by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature |