| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4709011 | A | Permeability of the compound incubated for 165 mins by PAMPA-BBB assay | 11 | ALA4706524 | assay format | Scientific Literature | ||
| 2. | ALA4709015 | F | Vasorelaxant activity in OVA-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in absence of functional epithelium treated with compound after contraction stabilised | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
| 3. | ALA4709017 | F | Vasorelaxant activity in OVA-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in presence of functional epithelium treated with compound after contraction stabilised | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
| 4. | ALA4709018 | F | Vasorelaxant activity in non-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in absence of functional epithelium treated with compound after contraction stabilised | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
| 5. | ALA4709019 | F | Vasorelaxant activity in non-sensitized guinea pig-derived trachea assessed as decrease in CCh-induced tracheal tonic contraction in presence of functional epithelium | Cavia porcellus | 3 | ALA4706524 | tissue-based format | Scientific Literature | |
| 6. | ALA4709026 | P | Chemical stability of the compound in phosphate buffer at pH 2.0 measured upto 120 mins by HPLC-DAD analysis | 23 | ALA4706524 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4709027 | P | Chemical stability of the compound in phosphate buffer at pH 7.4 measured upto 120 mins by HPLC-DAD analysis | 23 | ALA4706524 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA4709028 | B | Inhibition of human recombinant PDE4A1A using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 4 | ALA4706524 | assay format | Scientific Literature | |
| 9. | ALA4709030 | B | Inhibition of human recombinant PDE4C using FAM-cAMP as substrate at 10 uM measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 24 | ALA4706524 | single protein format | Scientific Literature | |
| 10. | ALA4709031 | B | Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 5 | ALA4706524 | single protein format | Scientific Literature | |
| 11. | ALA4709033 | B | Inhibition of human recombinant PDE4A1A using FAM-cAMP as substrate at 10 uM measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 24 | ALA4706524 | assay format | Scientific Literature | |
| 12. | ALA4709034 | B | Inhibition of human recombinant PDE4B1 using FAM-cAMP as substrate at 10 uM measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 24 | ALA4706524 | single protein format | Scientific Literature | |
| 13. | ALA4709035 | B | Inhibition of human recombinant PDE4D3 using FAM-cAMP as substrate at 10 uM measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 24 | ALA4706524 | single protein format | Scientific Literature | |
| 14. | ALA4709043 | B | Inhibition of human recombinant PDE4B1 using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 1 | ALA4706524 | single protein format | Scientific Literature | |
| 15. | ALA4709044 | B | Inhibition of human recombinant PDE4C using FAM-cAMP as substrate measured after 1 hr by IMAP TR-FRET assay | Homo sapiens | 1 | ALA4706524 | single protein format | Scientific Literature |
The page will load shortly, Thanks for your patience!