# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4724651 | F | Antiproliferative activity against human TMD8 cells harboring MYD88 L265P mutant assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
2. | ALA4724653 | F | Antiproliferative activity against human OCILY10 cells harboring MYD88 L265P mutant assessed as inhibition of cell growth incubated for 72 hrs by CCK-8 assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA4724670 | B | Protac activity at CRBN/IRAK4 in human TMD8 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IRAK4 protein level at 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
4. | ALA4724671 | B | Protac activity at CRBN/IRAK4 in human OCILY10 cells harboring MYD88 L265P mutant assessed as induction of IRAK4 degradation by measuring reduction in IRAK4 protein level at 1 uM incubated for 24 hrs by Western blot analysis | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
5. | ALA4724672 | B | Protac activity at CRBN/IRAK4 in human OCILY10 cells assessed as inhibition of NFkappaB p65 phosphorylation at 2.5 to 20 uM incubated for 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |