# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4686182 | Binding | Inhibition of human COX1 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA | Homo sapiens | 24 | ALA4680229 | single protein format | Scientific Literature | |
2. | ALA4686183 | Binding | Inhibition of human COX2 assessed as reduction in PGF2alpha formation using arachidonic acid as substrate incubated for 10 mins by ELISA | Homo sapiens | 15 | ALA4680229 | single protein format | Scientific Literature | |
3. | ALA4686185 | ADME | Cytotoxicity against rat C6 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Rattus norvegicus | 23 | ALA4680229 | cell-based format | Scientific Literature | |
4. | ALA4686186 | ADME | Cytotoxicity against mouse BV-2 cells assessed as reduction in cell viability after 24 hrs by MTT assay | Mus musculus | 23 | ALA4680229 | cell-based format | Scientific Literature | |
5. | ALA4686187 | Functional | Inhibition of LPS-induced NO production in rat C6 cells incubated for 24 hrs by Griess reagent based assay | Rattus norvegicus | 15 | ALA4680229 | cell-based format | Scientific Literature | |
6. | ALA4686188 | Functional | Inhibition of LPS-induced NO production in mouse BV-2 cells incubated for 24 hrs by Griess reagent based assay | Mus musculus | 15 | ALA4680229 | cell-based format | Scientific Literature |