| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4721990 | F | Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced TNF-alpha production by measuring TNF-alpha level at 50 uM preincubated for 1 hr followed by LPS stimulation and measured after 24 hrs by ELISA (Rvb = 100 +/- 0%) | Mus musculus | 21 | cell-based format | Scientific Literature | ||
| 2. | ALA4721992 | F | Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced TNF-alpha production preincubated for 1 hr followed by LPS treatment and measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA4721993 | F | Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced IL-6 production preincubated for 1 hr followed by LPS treatment and measured after 24 hrs by ELISA | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4721994 | F | Anti-neuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitrite production preincubated for 1 hr followed by LPS treatment and measured after 24 hrs by Griess assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4721995 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-1beta mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 6. | ALA4721996 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-1beta mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA4721997 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-23p19 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA4721998 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-23p19 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 9. | ALA4721999 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-12p35 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA4722000 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-12p35 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 11. | ALA4722001 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-12p40 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA4722002 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL-12p40 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4722003 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced GM-CSF mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4722004 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced GM-CSF mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4722005 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced TNF mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4722006 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced TNF mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4722007 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL6 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 2 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4722008 | F | Anti-neuroinflammatory activity in primary mouse microglia cells assessed as reduction in LPS-induced IL6 mRNA expression at 100 uM preincubated for 1 hr followed by LPS treatment for 4 hrs by qPCR analysis | Mus musculus | 1 | cell-based format | Scientific Literature |
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