#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4701888	Functional	Antiproliferative activity against human KYSE-520 cells	Homo sapiens	20	ALA4699491	cell-based format	Scientific Literature
2.	ALA4701889	Binding	Allosteric inhibition of 6x-histidine tagged human SHP2 (Met1-L525 residues) expressed in Escherichia coli BL21 Star (DE3) using IRS1_pY1172(dPEG8)pY122 incubated for 30 mins by fluorescence based DIFMUP assay	Homo sapiens	29	ALA4699491	assay format	Scientific Literature
3.	ALA4701891	Binding	Allosteric inhibition of human SHP2 in human KYSE-520 cells assessed as reduction in ERK1/2 phosphorylation by fluorescence based assay	Homo sapiens	20	ALA4699491	cell-based format	Scientific Literature
4.	ALA4701893	Toxicity	Toxicity in mouse 3T3 cells under irradiation by NRU phototoxicity test	Mus musculus	3	ALA4699491	cell-based format	Scientific Literature
5.	ALA4701899	Physicochemical	Aqueous solubility of the compound at pH 6.8		18	ALA4699491	small-molecule physicochemical format	Scientific Literature
6.	ALA4701900	Physicochemical	Lipophilicity, logP of the compound		18	ALA4699491	small-molecule physicochemical format	Scientific Literature
7.	ALA4701901	Physicochemical	Distribution coefficient, logD of the compound		18	ALA4699491	small-molecule physicochemical format	Scientific Literature
8.	ALA4701902	Binding	Inhibition of human ERG by Q-patch assay	Homo sapiens	18	ALA4699491	single protein format	Scientific Literature
9.	ALA4701903	Functional	Allosteric inhibition of SHP2 in mouse xenografted with human KYSE-520 cells assessed as reduction in cellular p-ERK levels	Mus musculus	1	ALA4699491	assay format	Scientific Literature
10.	ALA5145443	Binding	Allosteric inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP and 2p-IRS1 peptide as substrates preincubated for 1 hr and followed by substrate addition at 10 uM and measured by microplate reader method relative to control	Homo sapiens	49	ALA5143569	single protein format	Scientific Literature
11.	ALA5145444	Binding	Allosteric inhibition of wild-type human SHP2 (1 to 535 residues) using DiFMUP and 2p-IRS1 peptide as substrates preincubated for 1 hr and followed by substrate addition and measured by microplate reader method	Homo sapiens	57	ALA5143569	single protein format	Scientific Literature
12.	ALA5145445	Binding	Allosteric inhibition of recombinant human SHP2 PTP domain (237 to 535 residues) using DiFMUP as substrate preincubated for 30 mins and followed by substrate addition and measured by microplate reader method	Homo sapiens	49	ALA5143569	single protein format	Scientific Literature
13.	ALA5145446	Binding	Allosteric inhibition of recombinant human SHP2 assessed as change in melting temperature by SYPRO orange dye based thermal shift assay	Homo sapiens	49	ALA5143569	single protein format	Scientific Literature