# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4734354 | F | Cytotoxicity against human A549 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4732094 | cell-based format | Scientific Literature | |
2. | ALA4734355 | F | Cytotoxicity against rat C6 cells assessed as cell viability measured after 24 hrs by MTT assay | Rattus norvegicus | 23 | ALA4732094 | cell-based format | Scientific Literature | |
3. | ALA4734356 | F | Cytotoxicity against human HepG2 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4732094 | cell-based format | Scientific Literature | |
4. | ALA4734357 | F | Cytotoxicity against human HT-29 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4732094 | cell-based format | Scientific Literature | |
5. | ALA4734358 | F | Cytotoxicity against human MCF7 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | ALA4732094 | cell-based format | Scientific Literature | |
6. | ALA4734359 | A | Cytotoxicity against mouse NIH3T3 cells assessed as cell viability measured after 24 hrs by MTT assay | Mus musculus | 23 | ALA4732094 | cell-based format | Scientific Literature | |
7. | ALA4734360 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human A549 cells | 23 | ALA4732094 | cell-based format | Scientific Literature | ||
8. | ALA4734361 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against rat C6 cells | 23 | ALA4732094 | cell-based format | Scientific Literature | ||
9. | ALA4734362 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human HepG2 cells | 23 | ALA4732094 | cell-based format | Scientific Literature | ||
10. | ALA4734363 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human HT-29 cells | 23 | ALA4732094 | cell-based format | Scientific Literature | ||
11. | ALA4734364 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human MCF7 cells | 23 | ALA4732094 | cell-based format | Scientific Literature | ||
12. | ALA4734365 | F | Inhibition of DNA synthesis in human HT-29 cells assessed as reduction in cell proliferation measured after 24 to 48 hrs by BrdU proliferation assay | Homo sapiens | 3 | ALA4732094 | cell-based format | Scientific Literature | |
13. | ALA4734366 | F | Inhibition of DNA synthesis in human MCF7 cells assessed as reduction in cell proliferation measured after 24 to 48 hrs by BrdU proliferation assay | Homo sapiens | 2 | ALA4732094 | cell-based format | Scientific Literature | |
14. | ALA4734367 | F | Inhibition of DNA synthesis in human HepG2 cells assessed as reduction in cell proliferation measured after 24 to 48 hrs by BrdU proliferation assay | Homo sapiens | 4 | ALA4732094 | cell-based format | Scientific Literature | |
15. | ALA4734368 | F | Inhibition of DNA synthesis in rat C6 cells assessed as reduction in cell proliferation measured after 24 to 48 hrs by BrdU proliferation assay | Rattus norvegicus | 6 | ALA4732094 | cell-based format | Scientific Literature | |
16. | ALA4734369 | F | Induction of apoptosis in human HT-29 cells assessed as viable cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 90.3%) | Homo sapiens | 3 | ALA4732094 | cell-based format | Scientific Literature | |
17. | ALA4734370 | F | Induction of apoptosis in human HT-29 cells assessed as early apoptotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 1.1%) | Homo sapiens | 3 | ALA4732094 | cell-based format | Scientific Literature | |
18. | ALA4734371 | F | Induction of apoptosis in human HT-29 cells assessed as late apoptotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 1.5%) | Homo sapiens | 3 | ALA4732094 | cell-based format | Scientific Literature | |
19. | ALA4734372 | F | Induction of apoptosis in human HT-29 cells assessed as necrotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 7.2%) | Homo sapiens | 3 | ALA4732094 | cell-based format | Scientific Literature | |
20. | ALA4734373 | F | Induction of apoptosis in human MCF7 cells assessed as viable cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 94.9%) | Homo sapiens | 2 | ALA4732094 | cell-based format | Scientific Literature |