#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4679878	B	Inhibition of HPGDS in human KU812 cells assessed as reduction in PGD2 level at 10 to 100 nM incubated for 24 hrs followed by A23187 treatment and measured after 30 mins and subsequent compound washout then further incubated for 6 hrs in compound-free medium by ELISA	Homo sapiens	3		cell-based format	Scientific Literature
2.	ALA4679879	P	Solubility of the compound		2		small-molecule physicochemical format	Scientific Literature
3.	ALA4679880	A	Permeability of the compound		2		assay format	Scientific Literature
4.	ALA4679881	B	Inhibition of HPGDS in human KU812 cells assessed as reduction in PGD2 level at 10 to 100 nM incubated for 24 hrs followed by A23187 treatment and measured after 30 mins by ELISA	Homo sapiens	3		cell-based format	Scientific Literature
5.	ALA4679883	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as induction of HPGDS degradation at 10 to 100 nM incubated for 24 hrs followed by compound washout and further incubated for 6 hrs in compound-free medium by Western blot analysis	Homo sapiens	2		cell-based format	Scientific Literature
6.	ALA4679884	B	Inhibition of recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 3 mins by spectrophotometric analysis	Homo sapiens	3		assay format	Scientific Literature
7.	ALA4679885	B	Binding affinity to recombinant human HPGDS expressed in Escherichia coli BL21 (DE3) measured after 1 hr by fluorescence polarization assay	Homo sapiens	3		assay format	Scientific Literature
8.	ALA4679886	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as induction of HPGDS degradation at 100 nM measured after 6 hrs in presence of ubiquitin-activating enzyme inhibitor MLN7243 by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
9.	ALA4679887	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as induction of HPGDS degradation at 100 nM measured after 6 hrs in presence of proteasome inhibitor MG132 by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
10.	ALA4679888	B	Competitive binding affinity to HPGDS in human KU812 cells assessed as induction of CRBN-mediated degradation of HPGDS at 100 nM after 6 hrs in presence of excess pomalidomide by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
11.	ALA4679891	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as induction of HPGDS degradation at 1 uM measured after 6 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
12.	ALA4679892	F	Effect on HPGDS mRNA expression in human KU812 cells up to 1000 nM measured after 6 hrs by SYBR green based qRT-PCR analysis	Homo sapiens	1		cell-based format	Scientific Literature
13.	ALA4679893	B	Protac activity at CRBN/Cyclin B1 in human KU812 cells assessed as decrease in cyclin B1 protein level by measuring protein turnover at 100 nM measured within 6 hrs in presence of protein synthesis inhibitor cycloheximide by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
14.	ALA4679894	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as decrease in HPGDS protein level by measuring protein turnover at 100 nM measured within 6 hrs in presence of protein synthesis inhibitor cycloheximide by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
15.	ALA4679895	B	Protac activity at CRBN/AKR1B1 in human KU812 cells assessed as reduction in AKR1B1 protein level up to 1000 nM measured after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
16.	ALA4679896	B	Protac activity at CRBN/MPGES-1 in human KU812 cells assessed as reduction in MPGES-1 protein level up to 1000 nM measured after 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
17.	ALA4679898	B	Protac activity at CRBN/HPGDS in human MEG01s cells assessed as reduction in HPGDS protein level up to 1000 nM measured after 6 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
18.	ALA4679901	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as reduction in HPGDS protein level at >=10 nM measured after 3 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
19.	ALA4679902	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as reduction in HPGDS protein level at 100 to 1000 nM measured after 3 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature
20.	ALA4679903	B	Protac activity at CRBN/HPGDS in human KU812 cells assessed as reduction in HPGDS protein level at >=10 nM measured after 6 to 24 hrs by Western blot analysis	Homo sapiens	1		cell-based format	Scientific Literature