| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4724819 | B | Binding affinity to human partial length BRD2-BD1 (K71 to N194 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 2. | ALA4724820 | B | Binding affinity to human partial length BRD3-BD1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 3. | ALA4724826 | B | Inhibition of BRD4-BD1 (unknown origin) by TR-FRET assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 4. | ALA4724827 | B | Inhibition of BRD4 in human PBMC assessed as reduction in LPS-induced TNFalpha secretion preincubated for 1 hr followed by LPS-stimulation and measured after 20 hrs by magnetic beads technique based assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 5. | ALA4724828 | B | Inhibition of recombinant human ERK5 using myelin basic protein as substrate by [gamm33P]ATP based HotSpot radiometric assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 6. | ALA4724829 | A | Stability of compound in human liver microsomes assessed as parent compound remaining after 1 hr | Homo sapiens | 7 | microsome format | Scientific Literature | ||
| 7. | ALA4724830 | B | Inhibition of human ERG stably expressed in CHO cells at holding potential of -80 mV incubated for 12 mins | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 8. | ALA4724831 | B | Binding affinity to human partial length BRD2-BD2 (E348 to D455 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 9. | ALA4724832 | B | Binding affinity to human partial length BRD3-BD2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 10. | ALA4724833 | B | Binding affinity to human partial length BRD4-BD1 (N44 to E168 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA4724834 | B | Binding affinity to human partial length BRD4-BD2 (K333 to E460 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 12. | ALA4724835 | B | Binding affinity to human partial length BRDT-BD1 (N21 to E137 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 13. | ALA4724836 | B | Binding affinity to human partial length BRDT-BD2 (K250 to E382 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 14. | ALA4724837 | B | Binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 15. | ALA4724838 | B | Binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system by BROMOscan method | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 16. | ALA4724839 | F | Inhibition of IL-6 production in LPS-induced human PBMC preincubated for 1 hr followed by LPS-stimulation and measured after 20 hrs by magnetic beads technique based assay | Homo sapiens | 14 | tissue-based format | Scientific Literature | ||
| 17. | ALA4724840 | F | Inhibition of MCP-1 production in LPS-induced human PBMC preincubated for 1 hr followed by LPS-stimulation and measured after 20 hrs by magnetic beads technique based assay | Homo sapiens | 14 | tissue-based format | Scientific Literature | ||
| 18. | ALA4724841 | B | Selectivity ratio of Kd for binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system to Kd for binding affinity to human partial length BRD2-BD1 (K71 to N194 residues) expressed in bacterial expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4724842 | B | Selectivity ratio of Kd for binding affinity to human partial length EP300 (A1040 to G1161 residues) expressed in bacterial expression system to Kd for binding affinity to human partial length BRD2-BD1 (K71 to N194 residues) expressed in bacterial expression system | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4724843 | B | Selectivity ratio of Kd for binding affinity to human partial length CREBBP (R1081 to G1197 residues) expressed in bacterial expression system to Kd for binding affinity to human partial length BRD2-BD2 (E348 to D455 residues) expressed in bacterial expression system | Homo sapiens | 1 | assay format | Scientific Literature |
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