# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA618247 | ADME | Amount of tecadenoson present after 30 min in the liver S-9 assay as determined by mass specanalysis; trace | Homo sapiens | 1 | ALA1137938 | tissue-based format | Scientific Literature | |
2. | ALA623451 | ADME | Compound remaining after incubation with 2 mg/mL of human liver microsomes at 37 degrees C for 30 min in a pH 7.4, 0.05 M phosphate buffer | Homo sapiens | 5 | ALA1137938 | microsome format | Scientific Literature | |
3. | ALA623895 | ADME | Maximum concentration in rat plasma after 5 mg/kg oral gavage | Rattus norvegicus | 2 | ALA1137938 | organism-based format | Scientific Literature | |
4. | ALA628645 | ADME | Concentration in rat plasma after 5 mg/kg oral gavage for 8 hours | Rattus norvegicus | 2 | ALA1137938 | organism-based format | Scientific Literature | |
5. | ALA625867 | ADME | Plasma half life in rat after 5 mg/kg oral gavage; 6-8 hours | Rattus norvegicus | 1 | ALA1137938 | organism-based format | Scientific Literature | |
6. | ALA877599 | ADME | Bioavailability in rat after 5 mg/kg oral gavage | Rattus norvegicus | 1 | ALA1137938 | organism-based format | Scientific Literature | |
7. | ALA640341 | Functional | Agonistic activity against adenosine A1 receptor in guinea pig isolated hearts | Cavia porcellus | 4 | ALA1137935 | assay format | Scientific Literature | |
8. | ALA645222 | Binding | Binding affinity against adenosine A1 receptor using [3H]CCPA in guinea pig DDT membrane; 167+/-38 | Cavia porcellus | 1 | ALA1137935 | assay format | Scientific Literature | |
9. | ALA640233 | Binding | Binding affinity against adenosine A1 receptor using [3H]CPX in guinea pig DDT membrane; 3612+/-1937 | Cavia porcellus | 1 | ALA1137935 | assay format | Scientific Literature | |
10. | ALA640250 | Functional | Stimulation of binding of [35S]GTP uM) | Cricetulus griseus | 30 | ALA1137938 | assay format | Scientific Literature | |
11. | ALA645034 | Binding | Binding affinity for adenosine A1 receptor determined using hamster DDT1 cell membranes with [3H]CCPA as radioligand | Cricetulus griseus | 30 | ALA1137938 | cell-based format | Scientific Literature | |
12. | ALA677060 | Functional | Binding affinity against GTPgammaS receptor using [35S]GTP-gamma-S, radioligand in guinea pig. | Cavia porcellus | 31 | ALA1137935 | assay format | Scientific Literature | |
13. | ALA684274 | Functional | Agonist-induced SH prolongation in guinea pig isolated heart was determined; 3-5 uM (Partial agonist) | Cavia porcellus | 5 | ALA1137938 | organism-based format | Scientific Literature | |
14. | ALA847950 | Binding | Selectivity towards A1 adenosine receptor as ratio of human adenosine A2a and adenosine A1 receptors | Homo sapiens | 5 | ALA1137938 | protein format | Scientific Literature | |
15. | ALA847951 | Binding | Selectivity towards A1 adenosine receptor as ratio of human adenosine A2b and adenosine A1 receptors | Homo sapiens | 5 | ALA1137938 | protein format | Scientific Literature | |
16. | ALA847952 | Binding | Selectivity towards A1 adenosine receptor as ratio of human adenosine A3 and adenosine A1 receptors | Homo sapiens | 5 | ALA1137938 | protein format | Scientific Literature |