# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4701576 | B | Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr before CD3 and CD28 stimulation for 20 hrs by AlphaLISA method | Homo sapiens | 9 | ALA4699477 | tissue-based format | Scientific Literature | |
2. | ALA4701577 | A | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 9 | ALA4699477 | microsome format | Scientific Literature | |
3. | ALA4701578 | A | Metabolic stability in mouse liver microsomes assessed as half life | Mus musculus | 9 | ALA4699477 | microsome format | Scientific Literature | |
4. | ALA4701579 | A | Metabolic stability in rat liver microsomes assessed as half life | Rattus norvegicus | 9 | ALA4699477 | microsome format | Scientific Literature | |
5. | ALA4701580 | B | Inhibition of GAL4-fused RORalpha (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
6. | ALA4701581 | B | Inhibition of GAL4-fused RORbeta (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
7. | ALA4701582 | B | Inverse agonist activity at RORgammat in mouse Th17 cells | Mus musculus | 1 | ALA4699477 | cell-based format | Scientific Literature | |
8. | ALA4701583 | B | Inverse agonist activity of PXR (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
9. | ALA4701584 | B | Inverse agonist activity of LXRalpha (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
10. | ALA4701585 | B | Inverse agonist activity of LXRbeta (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
11. | ALA4701586 | A | Metabolic stability in dog liver microsomes assessed as half life | Canis lupus familiaris | 1 | ALA4699477 | microsome format | Scientific Literature | |
12. | ALA4701587 | A | Metabolic stability in cynomolgous monkey liver microsomes assessed as half life | Macaca fascicularis | 1 | ALA4699477 | microsome format | Scientific Literature | |
13. | ALA4701588 | A | Inhibition of recombinant CYP1A2 (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
14. | ALA4701589 | A | Inhibition of recombinant CYP2C8 (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
15. | ALA4701590 | A | Inhibition of recombinant CYP2C9 (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
16. | ALA4701591 | A | Inhibition of recombinant CYP2C19 (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
17. | ALA4701592 | A | Inhibition of recombinant CYP2D6 (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
18. | ALA4701593 | A | Inhibition of recombinant CYP3A4 (unknown origin) | Homo sapiens | 1 | ALA4699477 | single protein format | Scientific Literature | |
19. | ALA4701594 | A | Permeability in human Caco-2 cells | Homo sapiens | 1 | ALA4699477 | cell-based format | Scientific Literature | |
20. | ALA4701595 | A | Efflux ratio in human Caco-2 cells | Homo sapiens | 1 | ALA4699477 | cell-based format | Scientific Literature |