| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4689777 | Binding | Displacement of [3H]-PGE2 from human EP3 expressed in Chem-1 cell membranes incubated for 2 hrs by TopCount scintillation plate reader analysis | Homo sapiens | 48 | ALA4680377 | cell membrane format | Scientific Literature | |
| 2. | ALA4689778 | Functional | Antagonist activity at human EP3 expressed in CHO cells assessed as suppression of sulprostone-induced inhibition of forskolin induced cAMP production measured after 30 mins by HTR-FRET assay | Homo sapiens | 48 | ALA4680377 | cell-based format | Scientific Literature | |
| 3. | ALA4689779 | ADME | Metabolic stability in human liver microsomes assessed as intrinsic clearance half life | Homo sapiens | 48 | ALA4680377 | microsome format | Scientific Literature | |
| 4. | ALA4689780 | ADME | Metabolic stability in rat liver microsomes assessed as intrinsic clearance half life | Rattus norvegicus | 48 | ALA4680377 | microsome format | Scientific Literature | |
| 5. | ALA4689781 | Physicochemical | Kinetic solubility of compound in PBS buffer | 48 | ALA4680377 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA4689782 | Physicochemical | Kinetic solubility of compound at pH 2 | 48 | ALA4680377 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA4689783 | ADME | Apparent permeability across apical to basolateral side in dog MDCK cells | Canis lupus familiaris | 20 | ALA4680377 | cell-based format | Scientific Literature |
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