# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4727784 | B | Inhibition of human cathepsin B assessed as residual activity at 10 uM using Z-Arg-Arg-pNA as substrate measured after 60 mins by spectrophotometric assay relative to control | Homo sapiens | 20 | ALA4725328 | single protein format | Scientific Literature | |
2. | ALA4727786 | B | Inhibition of recombinant human cathepsin K expressed in insect cells using Z-Leu-Arg-AMC as substrate measured after 60 mins by fluorimetric assay | Homo sapiens | 20 | ALA4725328 | cell-based format | Scientific Literature | |
3. | ALA4727787 | B | Inhibition of human cathepsin L using Phe-Arg-pNA as substrate measured after 60 mins by spectrophotometric assay | Homo sapiens | 19 | ALA4725328 | single protein format | Scientific Literature | |
4. | ALA4727788 | B | Inhibition of human cathepsin L assessed as residual activity at 10 uM using Phe-Arg-pNA as substrate measured after 60 mins by spectrophotometric assay relative to control | Homo sapiens | 20 | ALA4725328 | single protein format | Scientific Literature | |
5. | ALA4727789 | B | Inhibition of recombinant human cathepsin S expressed in insect cells using Z-Phe-Arg-AMC as substrate measured after 60 mins by fluorimetric assay | Homo sapiens | 20 | ALA4725328 | cell-based format | Scientific Literature | |
6. | ALA4727790 | B | Selectivity ratio of Ki for human cathepsin L to Ki for recombinant human cathepsin S expressed in insect cells | Homo sapiens | 2 | ALA4725328 | cell-based format | Scientific Literature | |
7. | ALA4727791 | B | Selectivity ratio of Ki for recombinant human cathepsin K expressed in insect cells to Ki for recombinant human cathepsin S expressed in insect cells | Homo sapiens | 2 | ALA4725328 | cell-based format | Scientific Literature | |
8. | ALA4727793 | B | Inhibition of recombinant human cathepsin S expressed in insect cells assessed as residual activity at 10 uM using Z-Phe-Arg-AMC as substrate measured after 60 mins by fluorimetric assay relative to control | Homo sapiens | 20 | ALA4725328 | cell-based format | Scientific Literature | |
9. | ALA4727794 | B | Inhibition of recombinant human cathepsin K expressed in insect cells assessed as residual activity at 10 uM using Z-Leu-Arg-AMC as substrate measured after 60 mins by fluorimetric assay relative to control | Homo sapiens | 20 | ALA4725328 | cell-based format | Scientific Literature |