| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4711173 | A | Cytotoxicity against mouse RAW264.7 cells assessed as cell survival up to 10 uM measured after 24 hrs by MTS assay relative to control | Mus musculus | 6 | cell-based format | Scientific Literature | ||
| 2. | ALA4711175 | B | Inhibition of recombinant human C-terminal His/FLAG-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using Boc-Lys(epsilon-Ac)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 3. | ALA4711176 | B | Inhibition of recombinant human full-length C-terminal FLAG-tagged HDAC2 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 4. | ALA4711177 | B | Inhibition of human recombinant C-terminal His-tagged HDAC3 (1 to 428 residues)/N-terminal GST-tagged NCOR2 (395 to 489 residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys(epsilon-Ac)-AMC as substrate measured after 90 mins by fluorescence assay | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 5. | ALA4711178 | B | Protac activity at CRBN/HDAC1 in mouse RAW264.7 cells assessed as induction of HDAC1 degradation at 10 uM by Western blot analysis | Mus musculus | 6 | cell-based format | Scientific Literature |
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