#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4682086	B	Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay	Homo sapiens	7	ALA4680110	cell-based format	Scientific Literature
2.	ALA4682087	B	Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-current amplitude in response to the depolarizing pulse by whole cell patch clamp assay	Homo sapiens	9	ALA4680110	cell-based format	Scientific Literature
3.	ALA4682088	B	Selectivity index, ratio of IC50 for inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes to IC50 for activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-current amplitude		4	ALA4680110	cell-based format	Scientific Literature
4.	ALA4682091	F	Analgesic activity in Sprague-Dawley rat model of PNL injury-induced neuropathic pain assessed as pain threshold elevation percentage at 15 nmol/kg, IM administered as single dose measured after 2 to 2.5 hrs post dose	Rattus norvegicus	8	ALA4680110	organism-based format	Scientific Literature
5.	ALA4682094	B	Inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay	Rattus norvegicus	8	ALA4680110	cell-based format	Scientific Literature
6.	ALA4682095	B	Inhibition of rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 uM at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay relative to control	Rattus norvegicus	2	ALA4680110	cell-based format	Scientific Literature
7.	ALA4682096	B	Inhibition of rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 uM at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay relative to control	Rattus norvegicus	2	ALA4680110	cell-based format	Scientific Literature
8.	ALA4682097	B	Inhibition of rat alpha2beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 uM at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay relative to control	Rattus norvegicus	2	ALA4680110	cell-based format	Scientific Literature
9.	ALA4682098	B	Inhibition of rat alpha2beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 uM at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay relative to control	Rattus norvegicus	2	ALA4680110	cell-based format	Scientific Literature
10.	ALA4682099	B	Inhibition of rat alpha4beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 uM at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay relative to control	Rattus norvegicus	2	ALA4680110	cell-based format	Scientific Literature
11.	ALA4682100	B	Inhibition of rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at 10 uM at -80 mV holding potential preincubated for 5 mins followed by Ach stimulation by two electrode voltage-clamp assay relative to control	Rattus norvegicus	2	ALA4680110	cell-based format	Scientific Literature
12.	ALA4682101	B	Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated Ba2+ peak-current amplitude in response to depolarizing pulse in presence of 1 uM GABAB receptor antagonist CGP55845 by whole cell patch clamp assay	Homo sapiens	3	ALA4680110	cell-based format	Scientific Literature
13.	ALA4682102	B	Inhibition of TTX-resistant sodium channel in Sprague-Dawley rat DRG neuron at 10 uM at 10 mV holding potential by whole cell patch clamp technique	Rattus norvegicus	3	ALA4680110	assay format	Scientific Literature
14.	ALA4682103	B	Inhibition of TTX-sensitive sodium channel in Sprague-Dawley rat DRG neuron at 10 uM at -10 mV holding potential by whole cell patch clamp technique	Rattus norvegicus	3	ALA4680110	tissue-based format	Scientific Literature
15.	ALA4682104	B	Selectivity index, ratio of IC50 for inhibition of rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes to IC50 for activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak Ba2+ current amplitude		5	ALA4680110	cell-based format	Scientific Literature
16.	ALA4682105	B	Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-current amplitude in response to depolarizing pulse at 1 nM by whole cell patch clamp assay relative to control	Homo sapiens	3	ALA4680110	cell-based format	Scientific Literature
17.	ALA4682107	B	Activation of human GABAB1/GABAB2 expressed in HEK293 cells co-transfected with rat CaV2.2 channel assessed as reduction in CaV2.2-mediated peak-current amplitude in response to depolarizing pulse at 1 nM in presence of with 10 uM baclofen by whole cell patch clamp assay relative to control	Homo sapiens	1	ALA4680110	cell-based format	Scientific Literature
18.	ALA4682108	B	Inhibition of rat CaV2.2 channel expressed in HEK293T cells assessed as reduction in CaV2.2-mediated peak-current amplitude in response to depolarizing pulse at 10 uM by whole cell patch clamp assay relative to control	Rattus norvegicus	1	ALA4680110	cell-based format	Scientific Literature