| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4688363 | B | Induction of microtubule depolymerisation in rat A-10 cell line measured after 18 hrs by indirect immunofluorescence method | Rattus norvegicus | 10 | tissue-based format | Scientific Literature | ||
| 2. | ALA4688364 | F | Antiproliferative activity against human MDA-MB-435 cell line assessed as inhibition of cell proliferation measured after 48 hrs by SRB assay | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
| 3. | ALA4688365 | F | Cytotoxicity against human U251 cell line assessed as inhibition of cell growth after 48 hrs by SRB assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 4. | ALA4688366 | B | Inhibition of bovine tubulin polymerization assessed as reduction in extent of assembly preincubated for 15 mins followed by addition of reaction mixture measured after 20 mins by turbidimetric assay | Bos taurus | 7 | assay format | Scientific Literature | ||
| 5. | ALA4688367 | B | Inhibition of [3H]colchicine binding to bovine tubulin at 5 uM measured after 10 mins by scintillation counting | Bos taurus | 7 | assay format | Scientific Literature | ||
| 6. | ALA4688368 | B | Inhibition of [3H]colchicine binding to bovine tubulin at 1 uM measured after 10 mins by scintillation counting | Bos taurus | 7 | assay format | Scientific Literature | ||
| 7. | ALA4688369 | F | Antiproliferative activity against human HeLa cells assessed as decrease in cell growth measured after 48 hrs by SRB method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 8. | ALA4688370 | B | Inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation measured after 48 hrs by SRB method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 9. | ALA4688371 | U | Relative resistance, ratio of IC50 for inhibition of beta3 Tubulin (unknown origin) expressed in human HeLa cell line assessed as inhibition of cell proliferation to IC50 antiproliferative activity against human HeLa cells | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 10. | ALA4688372 | F | Antiproliferative activity against human SK-OV-3 cells assessed as decrease in cell growth measured after 48 hrs by SRB method | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 11. | ALA4688373 | F | Antiproliferative activity against human SK-OV-3 MDR-1-6/6 cells expressing Pgp assessed as decrease in cell growth measured after 48 hrs by SRB method | Homo sapiens | 8 | tissue-based format | Scientific Literature | ||
| 12. | ALA4688374 | F | Relative resistance, ratio of IC50 for antiproliferative activity against human SK-OV-3 MDR-1-6/6 cells expressing Pgp to IC50 antiproliferative activity against human SK-OV-3 cells | Homo sapiens | 8 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!