# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4709468 | Binding | Inhibition of full length recombinant human N-terminal GST/His6-tagged PAK1 expressed in sf9 insect cells using tetra LRRWSLG as substrate preincubated for 20 min followed by [gamma33P]ATP addition and measured after 120 mins by Hotspot assay | Homo sapiens | 24 | ALA4706541 | cell-based format | Scientific Literature | |
2. | ALA4709501 | Functional | Antiproliferative activity against human MDA-MB-231 cells assessed as growth inhibition at 1 uM after 72 hrs by Cell Titer-Glo assay relative to control | Homo sapiens | 15 | ALA4706541 | cell-based format | Scientific Literature | |
3. | ALA4709502 | Functional | Antiproliferative activity against human HCT-116 cells assessed as growth inhibition at 1 uM after 72 hrs by Cell Titer-Glo assay relative to control | Homo sapiens | 15 | ALA4706541 | cell-based format | Scientific Literature |