# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700281 | B | Antagonist activity at integrin alphavbeta3 receptor in HUVEC cells assessed as inhibition of cell adhesion to human vitronectin at 50 uM preincubated for 30 mins followed by transferring to vitronectin coated plates and measured after 1 hr by DAPI staining based inverted fluorescence microscopic analysis | Homo sapiens | 4 | ALA4699422 | cell-based format | Scientific Literature | |
2. | ALA4700282 | F | Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 11 | ALA4699422 | cell-based format | Scientific Literature | |
3. | ALA4700284 | F | Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization preincubated for 2 hrs with LPS and 30 mins with cRGD followed by compound addition by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 2 | ALA4699422 | cell-based format | Scientific Literature | |
4. | ALA4700285 | F | Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization preincubated for 2 hrs with LPS followed by compound addition in absence of cRGD by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 2 | ALA4699422 | cell-based format | Scientific Literature | |
5. | ALA4700286 | F | Agonist activity at PAR2 in human EA.hy926 cells assessed as stimulation of calcium mobilization treated with cRGD for 30 mins prior to compound addition by Fluo-4-AM dye-based FLIPR assay | Homo sapiens | 2 | ALA4699422 | cell-based format | Scientific Literature |