| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4704485 | B | Inhibition of recombinant human MMP12 catalytic domain (Gly106 to Gly263 residues) expressed in Escherichia coli BL21 Codon Plus cells using 5-FAM/QXL520 FRET peptide as substrate preincubated for 15 mins followed by substrate addition and measured at 3 mins interval for 60 mins by fluorescence assay | Homo sapiens | 27 | cell-based format | Scientific Literature | ||
| 2. | ALA4704496 | F | Protection against porcine elastase-induced emphysema in ip dosed C57BL/6 mouse model assessed as effect on total BALF cellularity/influx administered once daily for 7 days measured 21 days post initial elastase instillation | Mus musculus | 3 | organism-based format | Scientific Literature | ||
| 3. | ALA4704497 | F | Protection against porcine elastase-induced emphysema in ip dosed C57BL/6 mouse model assessed as decrease in emphysema-like pathology administered once daily for 7 days measured 21 days post initial elastase instillation by H and E staining based light microscopic analysis | Mus musculus | 3 | organism-based format | Scientific Literature |
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