| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4723216 | A | Plasma protein binding in CD1 mouse at 5 uM measured after 4 hrs by LC-MS/MS based rapid equilibrium dialysis method | Mus musculus | 27 | cell-free format | Scientific Literature | ||
| 2. | ALA4723280 | A | Permeability of the compound in human Caco-2 cells assessed as compound recovery at 10 uM measured after 2 hrs by LC/MS/MS analysis | Homo sapiens | 40 | cell-based format | Scientific Literature | ||
| 3. | ALA4723285 | A | Drug metabolism in rat liver microsome assessed as reduction of aldehyde group at 10 mM measured after 15 mins in presence of NADPH by LC-MS analysis | Rattus norvegicus | 40 | microsome format | Scientific Literature | ||
| 4. | ALA4723286 | A | Drug metabolism in human liver microsome assessed as reduction of aldehyde group at 10 mM measured after 15 mins in presence of NADPH by LC-MS analysis | Homo sapiens | 40 | microsome format | Scientific Literature | ||
| 5. | ALA4723292 | A | Hepatic extraction ratio in rat liver microsomes preincubated for 3 mins followed by NADPH addition and measured after 60 mins | Rattus norvegicus | 80 | microsome format | Scientific Literature | ||
| 6. | ALA4723295 | B | Inhibition of FGFR4 in mouse BAF3 cells assessed as decrease in FGFR4 phosphorylation incubated for 40 mins | Mus musculus | 76 | cell-based format | Scientific Literature | ||
| 7. | ALA4723314 | B | Inhibition of recombinant non-phosphorylated FGFR4 kinase domain (442 to 753) (unknown origin) expressed in Sf9 insect cells using 5-Fluo-Ahx-KKKKEEIYFFFG-NH2 peptide as substrate in presence of ATP measured after 60 mins by caliper microfluidic mobility shift assay | Homo sapiens | 82 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!