| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4734354 | F | Cytotoxicity against human A549 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 2. | ALA4734355 | F | Cytotoxicity against rat C6 cells assessed as cell viability measured after 24 hrs by MTT assay | Rattus norvegicus | 23 | cell-based format | Scientific Literature | ||
| 3. | ALA4734356 | F | Cytotoxicity against human HepG2 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 4. | ALA4734357 | F | Cytotoxicity against human HT-29 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 5. | ALA4734358 | F | Cytotoxicity against human MCF7 cells assessed as cell viability measured after 24 hrs by MTT assay | Homo sapiens | 23 | cell-based format | Scientific Literature | ||
| 6. | ALA4734359 | A | Cytotoxicity against mouse NIH3T3 cells assessed as cell viability measured after 24 hrs by MTT assay | Mus musculus | 23 | cell-based format | Scientific Literature | ||
| 7. | ALA4734360 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human A549 cells | 23 | cell-based format | Scientific Literature | |||
| 8. | ALA4734361 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against rat C6 cells | 23 | cell-based format | Scientific Literature | |||
| 9. | ALA4734362 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human HepG2 cells | 23 | cell-based format | Scientific Literature | |||
| 10. | ALA4734363 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human HT-29 cells | 23 | cell-based format | Scientific Literature | |||
| 11. | ALA4734364 | T | Selectivity index, ratio of IC50 for cytotoxicity against mouse NIH3T3 cells to IC50 for cytotoxicity against human MCF7 cells | 23 | cell-based format | Scientific Literature | |||
| 12. | ALA4734367 | F | Inhibition of DNA synthesis in human HepG2 cells assessed as reduction in cell proliferation measured after 24 to 48 hrs by BrdU proliferation assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 13. | ALA4734368 | F | Inhibition of DNA synthesis in rat C6 cells assessed as reduction in cell proliferation measured after 24 to 48 hrs by BrdU proliferation assay | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA4734377 | F | Induction of apoptosis in human HepG2 cells assessed as viable cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 87.8%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 15. | ALA4734378 | F | Induction of apoptosis in human HepG2 cells assessed as early apoptotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 0.9%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 16. | ALA4734379 | F | Induction of apoptosis in human HepG2 cells assessed as late apoptotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 8.7%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 17. | ALA4734380 | F | Induction of apoptosis in human HepG2 cells assessed as necrotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method (Rvb = 4.6%) | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 18. | ALA4734381 | F | Induction of apoptosis in rat C6 cells assessed as apoptotic cells at IC50 concentration measured after 24 hrs by Annexin V-FITC/PI staining based flow cytometry method relative to control | Rattus norvegicus | 6 | cell-based format | Scientific Literature | ||
| 19. | ALA4734382 | A | Drug metabolism in human HepG2 cells assessed as amine metabolite formation after 24 hrs by LCMS-IT-TOF analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4734383 | A | Induction of CYP1A1/CYP1A2 in SEAP-induced human HepG2 cells at 1 uM preincubated for 30 mins followed by addition of substrate and measured after 30 mins by luminescence assay relative to 3-methylcollantrate | Homo sapiens | 2 | assay format | Scientific Literature |
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