| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4709829 | F | Antagonist activity at human D2 receptor expressed in CHO-K1 cells assessed as inhibition of dopamine-induced calcium flux at 10 uM incubated for 60 mins at 37 degC followed by 15 mins incubation at room temperature and subsequent dopamine addition by calcium 4 dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA4709831 | B | Binding affinity to D3 receptor (unknown origin) | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 3. | ALA4709840 | B | Displacement of [3H]spiperone from D2 receptor in rat striatum measured after 15 mins by liquid scintillation counting method | Rattus norvegicus | 32 | tissue-based format | Scientific Literature | ||
| 4. | ALA4709841 | B | Displacement of [3H](+)8-OH-DPAT from rat cerebral cortex 5HT1A receptor measured after 30 mins by liquid scintillation counting method | Rattus norvegicus | 32 | tissue-based format | Scientific Literature | ||
| 5. | ALA4709842 | B | Displacement of [3H]ketanserin from rat cerebral cortex 5HT2A receptor measured after 15 mins by liquid scintillation counting method | Rattus norvegicus | 32 | tissue-based format | Scientific Literature | ||
| 6. | ALA4709843 | A | Displacement of [3H]prazosin from rat cerebral cortex alpha1 adrenergic receptor measured after 60 mins by liquid scintillation counting method | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 7. | ALA4709844 | A | Displacement of [3H]mesulergine from rat cerebral cortex 5HT2C receptor measured after 15 mins by liquid scintillation counting method | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 8. | ALA4709845 | A | Displacement of [3H]pyrilamine from guinea pig cerebellum histamine H1 receptor measured after 60 mins by liquid scintillation counting method | Cavia porcellus | 4 | tissue-based format | Scientific Literature | ||
| 9. | ALA4709846 | B | Displacement of [3H]5-CT from rat cerebral cortex 5HT7 receptor measured after 30 mins by liquid scintillation counting method | Rattus norvegicus | 4 | tissue-based format | Scientific Literature | ||
| 10. | ALA4709847 | B | Displacement of [3H]lysergic acid diethylamide from human recombinant 5HT6 receptor stably expressed in CHO cell membranes measured after 30 mins by liquid scintillation counting method | Homo sapiens | 4 | cell membrane format | Scientific Literature | ||
| 11. | ALA4709848 | B | Inhibition of human ERG expressed in HEK293 cells by whole-cell patch clamp method | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 12. | ALA4709849 | T | Cardiotoxicity in anesthetized guinea pig assessed as QT prolongation at 0.04 to 0.4 mg/kg, ip | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA4709850 | T | Cardiotoxicity in anesthetized guinea pig assessed as cardiac liability at 0.04 to 0.4 mg/kg, ip | Cavia porcellus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA4709851 | F | Agonist activity at human D2 receptor expressed in CHO-K1 cells at 10 uM by calcium 4 dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA4709853 | F | Antagonist activity at human D2 receptor expressed in CHO-K1 cells assessed as inhibition of dopamine-induced calcium flux incubated for 60 mins at 37 degC followed by 15 mins incubation at room temperature and subsequent dopamine addition by calcium 4 dye based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA4709854 | F | Agonist activity at human 5HT1A receptor expressed in CHO-K1 cells at 10 uM by calcium 4 dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA4709856 | F | Antagonist activity at human 5HT1A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux at 10 uM incubated for 60 mins at 37 degC followed by 15 mins incubation at room temperature and subsequent 5HT addition by calcium 4 dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA4709857 | F | Antagonist activity at human 5HT1A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux incubated for 60 mins at 37 degC followed by 15 mins incubation at room temperature and subsequent 5HT addition by calcium 4 dye based FLIPR assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA4709858 | F | Agonist activity at human 5HT2A receptor expressed in CHO-K1 cells at 10 uM by calcium 4 dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA4709860 | F | Antagonist activity at human 5HT2A receptor expressed in CHO-K1 cells assessed as inhibition of 5HT-induced calcium flux at 10 uM incubated for 60 mins at 37 degC followed by 15 mins incubation at room temperature and subsequent 5HT addition by calcium 4 dye based FLIPR assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature |
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