| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4669632 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with intact mitochondrial membrane potential at 25 uM by JC-10 staining-based flow cytometric analysis (Rvb = 77.48 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 2. | ALA4669633 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with mitochondrial membrane potential collapse at 25 uM by JC-10 staining-based flow cytometric analysis (Rvb = 22.17 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 3. | ALA4669634 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with intact mitochondrial membrane potential at 10 uM by JC-10 staining-based flow cytometric analysis (Rvb = 77.48 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 4. | ALA4669635 | Functional | Induction of mitochondrial membrane potential loss in human HelaM cells assessed as cell population with mitochondrial membrane potential collapse at 10 uM by JC-10 staining-based flow cytometric analysis (Rvb = 22.17 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 5. | ALA4669636 | Functional | Induction of apoptosis in human HelaM cells assessed as viable cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 93.33 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 6. | ALA4669637 | Functional | Induction of apoptosis in human HelaM cells assessed as necrotic cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.55 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 7. | ALA4669638 | Functional | Induction of apoptosis in human HelaM cells assessed as late apoptotic cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.62 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 8. | ALA4669639 | Functional | Induction of apoptosis in human HelaM cells assessed as early apoptotic cells at 25 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.5 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 9. | ALA4669640 | Functional | Induction of apoptosis in human HelaM cells assessed as viable cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 93.33 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 10. | ALA4669641 | Functional | Induction of apoptosis in human HelaM cells assessed as necrotic cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 4.55 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 11. | ALA4669642 | Functional | Induction of apoptosis in human HelaM cells assessed as late apoptotic cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 0.62 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 12. | ALA4669643 | Functional | Induction of apoptosis in human HelaM cells assessed as early apoptotic cells at 10 uM after 24 hrs by V-FITC/propidium iodide staining-based flow cytometric analysis (Rvb = 1.5 %) | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 13. | ALA4669644 | Functional | Potency index, ratio of doxorubicin IC50 to compound IC50 for cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 3 | ALA4665747 | cell-based format | Scientific Literature | |
| 14. | ALA4669645 | Unassigned | Selectivity index, ratio of IC50 for human chang liver cells to IC50 for human HelaM cells | Homo sapiens | 5 | ALA4665747 | assay format | Scientific Literature | |
| 15. | ALA4669646 | ADME | Cytotoxicity against human Chang liver cells assessed as reduction in cell viability after 24 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 5 | ALA4665747 | cell-based format | Scientific Literature | |
| 16. | ALA4669647 | ADME | Cytotoxicity against human WI-38 cells assessed as reduction in cell viability after 24 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 5 | ALA4665747 | cell-based format | Scientific Literature | |
| 17. | ALA4669648 | Functional | Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 5 | ALA4665747 | cell-based format | Scientific Literature | |
| 18. | ALA4669649 | Functional | Cytotoxicity against human HelaM cells assessed as reduction in cell viability after 24 hrs by DAPI staining-based fluorescence assay | Homo sapiens | 5 | ALA4665747 | cell-based format | Scientific Literature |
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