# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4714284 | ADME | Agonist activity at 5-HT2BR (unknown origin) transfected in human HEK293 cells by IP3 accumulation assay | Homo sapiens | 17 | ALA4706699 | cell-based format | Scientific Literature | |
2. | ALA4714285 | ADME | Agonist activity at 5-HT2BR (unknown origin) transfected in human HEK293 cells at 10 uM by IP3 accumulation assay relative to control | Homo sapiens | 13 | ALA4706699 | cell-based format | Scientific Literature | |
3. | ALA4714286 | Functional | Agonist activity at 5-HT2CR (unknown origin) transfected in human HEK293 cells at 10 uM by IP3 accumulation assay relative to control | Homo sapiens | 15 | ALA4706699 | cell-based format | Scientific Literature | |
4. | ALA4714287 | Functional | Agonist activity at 5-HT2CR (unknown origin) transfected in human HEK293 cells by IP3 accumulation assay | Homo sapiens | 17 | ALA4706699 | cell-based format | Scientific Literature | |
5. | ALA4714288 | Binding | Displacement of [125I]-DOI from recombinant human 5HT2CR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assay | Homo sapiens | 10 | ALA4706699 | cell-based format | Scientific Literature | |
6. | ALA4714289 | ADME | Displacement of [3H]-LSB from recombinant human 5HT2BR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assay | Homo sapiens | 10 | ALA4706699 | cell-based format | Scientific Literature | |
7. | ALA4714290 | ADME | Displacement of [3H]-DOI from recombinant human 5HT2AR transfected in human HEK293 cells incubated for 45 mins by radioligand binding assay | Homo sapiens | 10 | ALA4706699 | cell-based format | Scientific Literature | |
8. | ALA4714291 | ADME | Metabolic stability in rat liver microsomes assessed as parent compound remaining at 1 uM incubated for 45 mins | Rattus norvegicus | 7 | ALA4706699 | microsome format | Scientific Literature | |
9. | ALA4714292 | ADME | Metabolic stability in human liver microsomes assessed as parent compound remaining at 1 uM incubated for 45 mins | Homo sapiens | 7 | ALA4706699 | microsome format | Scientific Literature |