| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4722533 | Functional | Cell cycle arrest in human U2OS cells assessed as accumulation at S phase at 0.6 uM measured after 24 hrs by propidium iodide staining based flow cytometry (Rvb = 24%) | Homo sapiens | 1 | ALA4715837 | cell-based format | Scientific Literature | |
| 2. | ALA4722534 | ADME | Binding affinity at Tel21 G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 6 uM by circular dichroism spectrophotometric method | Not specified | 4 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 3. | ALA4722535 | Binding | Binding affinity at Tel45 G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 6 uM by circular dichroism spectrophotometric method | Not specified | 4 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 4. | ALA4722536 | Binding | Binding affinity at Tel45 G4 quadruplex DNA (unknown origin) assessed as enhancement of emission peak intensity at 470 nm at 1 uM by fluorescence spectroscopic analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 5. | ALA4722537 | Binding | Binding affinity at Tel45 G4 quadruplex DNA (unknown origin) by fluorescence spectroscopic analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 6. | ALA4722538 | ADME | Binding affinity at Tel21 G4 quadruplex DNA (unknown origin) by fluorescence spectroscopic analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 7. | ALA4722539 | ADME | Binding affinity to hairpin duplex DNA (unknown origin) by fluorescence spectroscopic analysis | Not specified | 1 | ALA4715837 | assay format | Scientific Literature | |
| 8. | ALA4722540 | Binding | Binding affinity at Tel45 G4 quadruplex DNA (unknown origin) assessed as appearance of new long-lived unquenched species by time resolved fluorescence assay | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 9. | ALA4722541 | ADME | Binding affinity at Tel21 G4 quadruplex DNA (unknown origin) by time resolved fluorescence analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 10. | ALA4722542 | ADME | Binding affinity to hairpin duplex DNA (unknown origin) by time resolved fluorescence analysis | Not specified | 1 | ALA4715837 | assay format | Scientific Literature | |
| 11. | ALA4722543 | Binding | Binding affinity to Tel45 G4 quadruplex DNA (unknown origin) assessed as compound-DNA complex formation at stoichiometry ratio of 1:1 by job-plot analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 12. | ALA4722544 | Binding | Binding affinity to 2-Ap25 labelled Tel45 G4 quadruplex DNA (unknown origin) up to 10 uM by fluorescence titration assay | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 13. | ALA4722545 | Binding | Binding affinity to 2-Ap1 labelled Tel45 G4 quadruplex DNA (unknown origin) up to 10 uM by fluorescence titration assay | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 14. | ALA4722546 | Binding | Binding affinity to 2-Ap46 labelled Tel45 G4 quadruplex DNA (unknown origin) up to 10 uM by fluorescence titration assay | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 15. | ALA4722547 | Binding | Binding affinity at Tel45-6 mutant G4 quadruplex DNA (unknown origin) by fluorescence spectroscopic analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 16. | ALA4722548 | Binding | Binding affinity at Tel45-9 mutant G4 quadruplex DNA (unknown origin) by fluorescence spectroscopic analysis | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 17. | ALA4722549 | ADME | Binding affinity at Tel45-6 mutant G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 6 uM by circular dichroism spectrophotometric method | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 18. | ALA4722550 | ADME | Binding affinity at Tel45-9 mutant G4 quadruplex DNA (unknown origin) assessed as change in melting temperature at 6 uM by circular dichroism spectrophotometric method | Not specified | 1 | ALA4715837 | nucleic acid format | Scientific Literature | |
| 19. | ALA4722551 | Functional | Cytotoxicity against human U2OS cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay | Homo sapiens | 2 | ALA4715837 | cell-based format | Scientific Literature | |
| 20. | ALA4722552 | ADME | Cytotoxicity against human BJ cells assessed as reduction in cell viability measured after 24 hrs by CCK8 assay | Homo sapiens | 1 | ALA4715837 | cell-based format | Scientific Literature |
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