# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4669390 | B | Binding affinity to AChE (unknown origin) assessed as dissociation constant by SPR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
2. | ALA4669391 | A | Cytotoxicity against HEL 299 cells by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
3. | ALA4669392 | A | Permeability in human Caco-2 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
4. | ALA4669393 | U | Stability of compound in intestinal juice | 1 | assay format | Scientific Literature | |||
5. | ALA4669394 | A | Metabolic stability in human plasma | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
6. | ALA4669395 | A | Permeability of compound by PAMPA-BBB assay | 2 | assay format | Scientific Literature | |||
7. | ALA4669396 | P | Stability of compound in gastric fluid | 1 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA4669397 | F | Protection against amyloid beta oligomer-induced cytotoxicity in human SH-SY5Y cells expressing wild-type Tau assessed as cell viability at 10 uM by MTT assay | Homo sapiens | 5 | cell-based format | Scientific Literature | ||
9. | ALA4669398 | B | Binding affinity to tau (unknown origin) assessed as dissociation constant by microscale thermophoresis assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
10. | ALA4669399 | B | Binding affinity to tau (unknown origin) assessed as dissociation constant by isothermal titration calorimetry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
11. | ALA4669400 | B | Binding affinity to tau (unknown origin) assessed as exothermal interaction by isothermal titration calorimetry | Homo sapiens | 1 | single protein format | Scientific Literature | ||
12. | ALA4669401 | B | Binding affinity to tau (unknown origin) assessed as dissociation constant by SPR analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA4669402 | B | Inhibition of tau oligomerization in human SY-SH5H cells by TR-FRET assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
14. | ALA4669403 | B | Mixed inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by UV-vis spectrophotometry based Lineweaver-burk plot analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
15. | ALA4669404 | B | Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate by UV-vis spectrophotometry based Ellman's method | Homo sapiens | 2 | single protein format | Scientific Literature |