# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4688056 | B | Inhibition of porcine pancreatic lipase preincubated for 10 mins followed by 4-MUO addition and measured at 60 sec interval for 40 mins by multi plate micro plate reader | Sus scrofa | 32 | single protein format | Scientific Literature | ||
2. | ALA4711500 | B | Inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrate addition measured after 20 mins by fluorescence analysis | Homo sapiens | 18 | microsome format | Scientific Literature | ||
3. | ALA4711501 | B | Inhibition of hCES1A in human liver microsome assessed as reduction in D-Iuciferin methyl ester hydrolysis preincubated for 10 mins followed by substrate addition measured after 10 mins by luminescence analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
4. | ALA4711502 | B | Inhibition of BChE in human plasma assessed as reduction in butyrylthiocholineiodide hydrolysis preincubated for 3 mins followed by substrate addition | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
5. | ALA4711503 | B | Mixed inhibition of hCES2A in human liver microsome assessed as reduction in fluorescein diacetate hydrolysis preincubated for 10 mins followed by substrate addition measured after 20 mins by Lineweave-Burk plots analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
6. | ALA4711504 | B | Inhibition of hCES2A in human HepG2 cells assessed as reduction in fluorogenic substrate NCEN hydrolysis preincubated for 1 hr followed by substrate addition measured after 45 mins by fluorescence analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
7. | ALA4711505 | A | Metabolic stability at phase 1 in human liver microsomes assessed as half life at 10 uM by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature | ||
8. | ALA4711506 | A | Metabolic stability at phase 2 in human liver microsomes assessed as half life at 10 uM by LC-MS/MS analysis | Homo sapiens | 2 | microsome format | Scientific Literature |