| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4775510 | B | Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes at 0.1 nM after 4 days by NBT reduction assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA4775514 | B | Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reduction assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA4775515 | B | Potency index, ratio of EC50 for lithocholic acid to EC50 for test compound for agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reduction assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA4775516 | B | Potency index, ratio of EC50 for 1-alpha,25-(OH)2D3 to EC50 for test compound for agonist activity at VDR in human HL60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days by NBT reduction assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4775517 | B | Agonist activity at VDR in human HL-60 cells assessed as induction of cell differentiation of promyelocytes to monocytes after 4 days in presence of 1 uM CYP24 inhibitor ketoconazole by NBT reduction assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA4775518 | B | Displacement of [3H]-1-alpha,25-(OH)2D3 from bovine thymus VDR incubated for 18 hrs by competitive binding assay | Bos taurus | 3 | single protein format | Scientific Literature | ||
| 7. | ALA4775519 | B | Agonist activity at human VDR expressed in African green monkey COS7 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA4775520 | B | Agonist activity at human VDR expressed in HEK293 cells expressing mouse osteopontin VDRE assessed as induction of receptor transactivation incubated for 16 hrs by luciferase reporter gene assay | Homo sapiens | 3 | cell-based format | Scientific Literature |
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