# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4770333 | Functional | Antiproliferative activity against human CAPAN-1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | ALA4765331 | cell-based format | Scientific Literature | |
2. | ALA4770334 | Functional | Antiproliferative activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | ALA4765331 | cell-based format | Scientific Literature | |
3. | ALA4770335 | Functional | Antiproliferative activity against human NCI-H460 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | ALA4765331 | cell-based format | Scientific Literature | |
4. | ALA4770336 | Functional | Antiproliferative activity against human HL-60 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | ALA4765331 | cell-based format | Scientific Literature | |
5. | ALA4770337 | Functional | Antiproliferative activity against human K562 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | ALA4765331 | cell-based format | Scientific Literature | |
6. | ALA4770338 | Functional | Antiproliferative activity against P-gp-positive/doxorubicin-resistant human K562/4 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 10 | ALA4765331 | tissue-based format | Scientific Literature | |
7. | ALA4770339 | Functional | Antiproliferative activity against human HCT-116 cells with inactivated p53 gene assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 10 | ALA4765331 | cell-based format | Scientific Literature | |
8. | ALA4770340 | ADME | Cytotoxicity against human TERT-RPE1 cells assessed as inhibition of cell proliferation measured after 72 hrs by MTT assay | Homo sapiens | 26 | ALA4765331 | cell-based format | Scientific Literature | |
9. | ALA4770342 | Functional | Resistance index, ratio of IC50 for human P-gp-positive/Doxorubicin-resistant K562/4 cells to IC50 for human K562 cells | Homo sapiens | 10 | ALA4765331 | assay format | Scientific Literature | |
10. | ALA4770343 | Functional | Resistance index, ratio of IC50 for human HCT-116 cells to IC50 for human HCT-116 cells with inactivated p53 | Homo sapiens | 10 | ALA4765331 | assay format | Scientific Literature | |
11. | ALA4770344 | Binding | Binding affinity to calf thymus double stranded DNA at 10 uM measured after 5 mins by flourescence spectroscopy method | Bos taurus | 4 | ALA4765331 | tissue-based format | Scientific Literature | |
12. | ALA4770345 | Binding | Binding affinity to calf thymus DNA assessed as DNA intercalation by measuring decrease of negative DNA band at 245 nm at 50 uM by circular dichroism spectral analysis | Bos taurus | 4 | ALA4765331 | tissue-based format | Scientific Literature | |
13. | ALA4770346 | Binding | Binding affinity to calf thymus DNA assessed as binding constant by scatchard plot analysis | Bos taurus | 4 | ALA4765331 | tissue-based format | Scientific Literature | |
14. | ALA4770347 | Binding | Binding affinity to calf thymus DNA assessed as dissociation constant by scatchard plot analysis | Bos taurus | 4 | ALA4765331 | tissue-based format | Scientific Literature | |
15. | ALA4770348 | Binding | Binding affinity to calf thymus DNA assessed as stoichiometry ratio of compound-DNA complex formation by scatchard plot analysis | Bos taurus | 4 | ALA4765331 | tissue-based format | Scientific Literature |