# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4774623 | A | Induction of platelet aggregation in human platelet rich plasma at plasma peak concentration of 10 times anti-thrombosis ED50 measured after 10 mins by light transmission aggregometry | Homo sapiens | 4 | cell-free format | Scientific Literature | ||
2. | ALA4774626 | B | Inhibition of factor 2a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
3. | ALA4774627 | B | Inhibition of factor 7a (unknown origin) at IC50 using pefachrome factor VIIa as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
4. | ALA4774628 | B | Inhibition of factor 10a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
5. | ALA4774629 | B | Inhibition of factor 11a (unknown origin) at IC50 using S-2366 as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
6. | ALA4774630 | B | Inhibition of factor 12a (unknown origin) at IC50 using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 10 | single protein format | Scientific Literature | ||
7. | ALA4774631 | B | Inhibition of factor 2a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
8. | ALA4774632 | B | Inhibition of factor 7a (unknown origin) at IC50 using pefachrome factor VIIa as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
9. | ALA4774633 | B | Inhibition of factor 10a (unknown origin) at IC50 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
10. | ALA4774634 | B | Inhibition of factor 11a (unknown origin) at IC50 using S-2366 as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
11. | ALA4774635 | B | Inhibition of factor 12a (unknown origin) at IC50 using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
12. | ALA4774636 | B | Inhibition of factor 2a (unknown origin) at IC90 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
13. | ALA4774637 | B | Inhibition of factor 11a (unknown origin) at IC90 using S-2366 as substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
14. | ALA4774638 | A | Inhibition of factor 12a (unknown origin) at IC90 using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III | Homo sapiens | 10 | single protein format | Scientific Literature | ||
15. | ALA4774639 | B | Inhibition of factor 10a (unknown origin) at IC90 preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins in presence of AT-III relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
16. | ALA4774641 | F | Anticoagulation activity in AT-III-deficient human plasma preincubated for 2 mins followed by APTT reagent and measured after 3 mins by coagulometric method | Homo sapiens | 5 | cell-free format | Scientific Literature | ||
17. | ALA4774642 | F | Anticoagulation activity in HCII-deficient human plasma preincubated for 2 mins followed by APTT reagent and measured after 3 mins by coagulometric method | Homo sapiens | 5 | cell-free format | Scientific Literature | ||
18. | ALA4774649 | A | Activation of factor 12a (unknown origin) up to 10 uM using kallikrein chromogenic substrate preincubated for 1 min followed by chromogenic substrate addition and measured for 2 mins | Homo sapiens | 4 | single protein format | Scientific Literature | ||
19. | ALA4774650 | A | Induction of platelet aggregation in rat wash platelet at plasma peak concentration of 10 times anti-thrombosis ED50 measured after 10 mins by light transmission aggregometry | Rattus norvegicus | 4 | cell-free format | Scientific Literature | ||
20. | ALA4774672 | F | Anticoagulation activity in human plasma assessed as drug level causing 20 times doubling of APTT preincubated for 2 mins followed by APTT reagent and measured after 3 mins by coagulometric method relative to dHG-5 | Homo sapiens | 9 | cell-free format | Scientific Literature |