# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4774839 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv measured after 7 days by resazurin microtiter assay | Mycobacterium tuberculosis | 31 | organism-based format | Scientific Literature | ||
2. | ALA4774840 | F | Antibacterial activity against Mycobacterium smegmatis measured after 7 days by resazurin microtiter assay | Mycolicibacterium smegmatis | 6 | organism-based format | Scientific Literature | ||
3. | ALA4774841 | F | Antibacterial activity against Mycobacterium aurum measured after 7 days by resazurin microtiter assay | Mycolicibacterium aurum | 6 | organism-based format | Scientific Literature | ||
4. | ALA4774842 | F | Antibacterial activity against Mycobacterium marinum measured after 7 days by resazurin microtiter assay | Mycobacterium marinum | 6 | organism-based format | Scientific Literature | ||
5. | ALA4774843 | F | Antibacterial activity against Mycobacterium bovis BCG measured after 7 days by resazurin microtiter assay | Mycobacterium tuberculosis | 6 | organism-based format | Scientific Literature | ||
6. | ALA4774844 | F | Antibacterial activity against Pseudomonas aeruginosa measured after 7 days by resazurin microtiter assay | Pseudomonas aeruginosa | 6 | organism-based format | Scientific Literature | ||
7. | ALA4774845 | F | Antibacterial activity against Acinetobacter baumannii measured after 7 days by resazurin microtiter assay | Acinetobacter baumannii | 6 | organism-based format | Scientific Literature | ||
8. | ALA4774846 | F | Antibacterial activity against Enterobacter aerogenes measured after 7 days by resazurin microtiter assay | Klebsiella aerogenes | 6 | organism-based format | Scientific Literature | ||
9. | ALA4774847 | F | Antibacterial activity against Enterobacter cloacae measured after 7 days by resazurin microtiter assay | Enterobacter cloacae | 6 | organism-based format | Scientific Literature | ||
10. | ALA4774848 | F | Antibacterial activity against Staphylococcus aureus measured after 7 days by resazurin microtiter assay | Staphylococcus aureus | 6 | organism-based format | Scientific Literature | ||
11. | ALA4774849 | F | Antibacterial activity against Klebsiella pneumoniae measured after 7 days by resazurin microtiter assay | Klebsiella pneumoniae | 6 | organism-based format | Scientific Literature | ||
12. | ALA4774850 | A | Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability measured after 24 to 48 hrs by Celltiter-glo assay | Chlorocebus sabaeus | 4 | cell-based format | Scientific Literature | ||
13. | ALA4774851 | A | Cytotoxicity against human macrophages assessed as reduction in cell viability measured after 6 days by Celltiter-glo assay | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
14. | ALA4774852 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv infected in human macrophages assessed as intracellular bacterial load at 0.5 MIC measured after 6 days (Rvb = 5.57 to 6.43 logCFU/ml) | Mycobacterium tuberculosis | 5 | organism-based format | Scientific Literature | ||
15. | ALA4774853 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv infected in human macrophages assessed as intracellular bacterial load at MIC measured after 6 days (Rvb = 5.57 to 6.43 logCFU/ml) | Mycobacterium tuberculosis | 5 | organism-based format | Scientific Literature | ||
16. | ALA4774854 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv infected in human macrophages assessed as intracellular bacterial load at 2 times MIC measured after 6 days (Rvb = 5.57 to 6.43 logCFU/ml) | Mycobacterium tuberculosis | 5 | organism-based format | Scientific Literature | ||
17. | ALA4774855 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv infected in human macrophages assessed as intracellular bacterial load at 4 times MIC measured after 6 days (Rvb = 5.57 to 6.43 logCFU/ml) | Mycobacterium tuberculosis | 5 | organism-based format | Scientific Literature | ||
18. | ALA4774856 | F | Antitubercular activity against FQ resistant Mycobacterium tuberculosis H37Rv harboring gyrA Ala-90-Val mutant measured after 7 days by resazurin microtiter assay | Mycobacterium tuberculosis | 7 | organism-based format | Scientific Literature | ||
19. | ALA4774857 | F | Antitubercular activity against FQ resistant Mycobacterium tuberculosis H37Rv harboring gyrA Asp-94-Gly mutant measured after 7 days by resazurin microtiter assay | Mycobacterium tuberculosis | 7 | organism-based format | Scientific Literature | ||
20. | ALA4774858 | F | Antitubercular activity against FQ resistant Mycobacterium tuberculosis H37Rv harboring gyrA Gly-88-Cys mutant measured after 7 days by resazurin microtiter assay | Mycobacterium tuberculosis | 7 | organism-based format | Scientific Literature |