#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA4775410	B	Competitive antagonist activity at human RXRA/RXRA expressed in African green monkey COS7 cells assessed as reduction in bexarotene-induced receptor activation by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
2.	ALA4775411	B	Competitive antagonist activity at human PPAR-gamma/RXRA expressed in African green monkey COS7 cells assessed as reduction in bexarotene-induced receptor activation by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
3.	ALA4775412	B	Competitive antagonist activity at human LXR-alpha/RXRA expressed in African green monkey COS7 cells assessed as reduction in bexarotene-induced receptor activation by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
4.	ALA4775413	B	Competitive antagonist activity at human RXRB/RXRB expressed in African green monkey COS7 cells assessed as reduction in bexarotene-induced receptor activation at 1 uM by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
5.	ALA4775414	B	Competitive antagonist activity at human RXRG/RXRG expressed in African green monkey COS7 cells assessed as reduction in bexarotene-induced receptor activation at 1 uM by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
6.	ALA4775415	B	Competitive antagonist activity at human PPAR-gamma/RXRA expressed in African green monkey COS7 cells assessed as reduction in PPAR pan-agonist TIPP-703-induced receptor activation at 10 uM by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
7.	ALA4775416	B	Competitive antagonist activity at human LXR-alpha/RXRA expressed in African green monkey COS7 cells assessed as reduction in LXR agonist T0901317 -induced receptor activation at 10 uM by RXRE-dependent luciferase reporter gene assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
8.	ALA4775417	B	Binding affinity to human RXR-alpha LBD incubated for 2 hrs by tryptophan fluorescence quenching assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
9.	ALA4775418	B	Displacement of [3H]-9-cis retinoic acid from recombinant human RXR-alpha LBD by liquid scintillation counting based competitive ligand binding assay	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
10.	ALA4775419	B	Binding affinity to human RXR-alpha by ITC analysis	Homo sapiens	2	ALA4765474	cell-based format	Scientific Literature
11.	ALA4775420	B	Binding affinity to human RXR-alpha assessed as induction of conformational changes by measuring theta222/theta208 ratio at 15 uM incubated for 2 hrs by CD spectroscopy	Homo sapiens	4	ALA4765474	cell-based format	Scientific Literature
12.	ALA4775422	B	Antagonist activity at RXR-alpha in mouse RAW264.7 cells assessed as supression of bexarotene-induced inhibition of LPS-induced NF-kappaB transcription by measuring NF-kappaB level at 0.1 to 10 uM incubated for 24 hrs by SEAP dependent NF-kappaB reporter assay	Mus musculus	1	ALA4765474	cell-based format	Scientific Literature
13.	ALA4775426	B	Antagonist activity at RXR-alpha in mouse RAW264.7 cells assessed as supression of bexarotene-induced inhibition of LPS-induced suppressed Nos2 gene expression at 10 uM incubated for 6 hrs by RT-PCR analysis	Mus musculus	1	ALA4765474	cell-based format	Scientific Literature
14.	ALA4775427	B	Antagonist activity at RXR-alpha in mouse RAW264.7 cells assessed as supression of bexarotene-induced inhibition of LPS-induced suppressed NO production at 1 uM incubated for 48 hrs by Griess assay	Mus musculus	1	ALA4765474	cell-based format	Scientific Literature
15.	ALA4775428	P	Solubility in pH 7.4 PBS at at 1 mM incubated for 6 hrs by HPLC analysis		1	ALA4765474	small-molecule physicochemical format	Scientific Literature
16.	ALA4775429	T	Toxicity in C57BL6/J mouse assessed as effect on body weight at 10 mg/kg/day, po for 14 days	Mus musculus	1	ALA4765474	organism-based format	Scientific Literature
17.	ALA4775430	T	Toxicity in C57BL6/J mouse assessed as effect on liver weight/body weight ratio at 10 mg/kg/day, po for 14 days	Mus musculus	1	ALA4765474	organism-based format	Scientific Literature
18.	ALA4775431	T	Toxicity in C57BL6/J mouse assessed as effect on plasma AST level at 10 mg/kg/day, po for 14 days	Mus musculus	1	ALA4765474	organism-based format	Scientific Literature
19.	ALA4775432	T	Toxicity in C57BL6/J mouse assessed as effect on plasma ALT level at 10 mg/kg/day, po for 14 days	Mus musculus	1	ALA4765474	organism-based format	Scientific Literature
20.	ALA5030469	B	Antagonist activity at human RXR-alpha expressed in African green monkey COS-1 cells assessed as reduction in NEt-TMN-induced receptor transactivation at 1 uM by luciferase reporter gene assay	Homo sapiens	3	ALA5029199	cell-based format	Scientific Literature