# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4711021 | Binding | Displacement of [3H]WIN35428 from DAT in Sprague-Dawley rat striatal membranes incubated for 120 mins by microbeta scintillation counting method | Rattus norvegicus | 43 | ALA4706586 | cell membrane format | Scientific Literature | |
2. | ALA4711022 | Binding | Displacement of [3H]citalopram from SERT in Sprague-Dawley rat midbrain membranes incubated for 60 mins by microbeta scintillation counting method | Rattus norvegicus | 43 | ALA4706586 | cell membrane format | Scientific Literature | |
3. | ALA4711023 | Binding | Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysis | Cavia porcellus | 43 | ALA4706586 | cell membrane format | Scientific Literature | |
4. | ALA4711024 | Binding | Selectivity ratio of Ki for SERT in Sprague-Dawley rat midbrain membranes to Ki for DAT in Sprague-Dawley rat striatum membranes | Rattus norvegicus | 43 | ALA4706586 | assay format | Scientific Literature | |
5. | ALA4711025 | Binding | Selectivity ratio of Ki for sigma 1 receptor in guinea pig brain cortex membranes to Ki for DAT in Sprague-Dawley rat striatum membranes | 42 | ALA4706586 | cell membrane format | Scientific Literature | ||
6. | ALA4711026 | Binding | Displacement of [3H]-N-methylspiperone from human D2L receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation counting method | Homo sapiens | 15 | ALA4706586 | cell membrane format | Scientific Literature | |
7. | ALA4711027 | Binding | Displacement of [3H]-N-methylspiperone from human D3 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation counting method | Homo sapiens | 15 | ALA4706586 | cell membrane format | Scientific Literature | |
8. | ALA4711028 | Binding | Displacement of [3H]-N-methylspiperone from human D4.4 receptor expressed in HEK293 cell membranes measured after 60 mins by microbeta scintillation counting method | Homo sapiens | 15 | ALA4706586 | cell membrane format | Scientific Literature | |
9. | ALA4711029 | Binding | Displacement of [3H]-Nisoxetine from NET in Sprague-Dawley rat frontal cortex membrane after 180 mins by microbeta scintillation counting method | Rattus norvegicus | 15 | ALA4706586 | cell membrane format | Scientific Literature | |
10. | ALA4711030 | ADME | Metabolic stability in rat liver microsomes assessed as compound remaining at 10 uM incubated for 60 mins in presence of NADPH regenerating system by LC-MS/MS analysis | Rattus norvegicus | 9 | ALA4706586 | microsome format | Scientific Literature | |
11. | ALA4711032 | ADME | Metabolic stability in rat liver microsomes assessed as compound remaining at 10 uM in presence of NADPH regenerating system by LC-MS/MS analysis | Rattus norvegicus | 9 | ALA4706586 | microsome format | Scientific Literature | |
12. | ALA4711034 | Toxicity | Toxicity in Swiss Webster mouse assessed as stimulation of ambulatory activity by measuring total distance travelled at 1 to 30 mg/kg, ip measured every 5 mins for 2 hrs | Mus musculus | 3 | ALA4706586 | organism-based format | Scientific Literature |