# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4700023 | ADME | Cytotoxicity against human ARPE-19 cells assessed as reduction in nuclei count measured after 10 days for Hoechst 33342 staining based microscopic analysis | Homo sapiens | 17 | ALA4699411 | cell-based format | Scientific Literature | |
2. | ALA4700024 | ADME | Cytotoxicity against human MRC5 cells assessed as reduction in nuclei count measured after 6 days for Hoechst 33342 staining based microscopic analysis | Homo sapiens | 17 | ALA4699411 | cell-based format | Scientific Literature | |
3. | ALA4700025 | Functional | Antiviral activity against Human cytomegalovirus infected in MRC5 cells measured after 6 days by fluorescence based microscopic analysis | Human betaherpesvirus 5 | 17 | ALA4699411 | cell-based format | Scientific Literature | |
4. | ALA4700026 | Functional | Antiviral activity against Human cytomegalovirus infected in ARPE-19 cells measured after 10 days by fluorescence based microscopic analysis | Human betaherpesvirus 5 | 17 | ALA4699411 | cell-based format | Scientific Literature | |
5. | ALA4700031 | Functional | Antiviral activity against Human cytomegalovirus infected in MRC5 cells assessed as reduction in viral plaque at 2.5 uM measured after 6 days by microscopic analysis relative to control | Human betaherpesvirus 5 | 1 | ALA4699411 | cell-based format | Scientific Literature | |
6. | ALA4700032 | Functional | Antiviral activity against Human cytomegalovirus infected in MRC5 cells assessed as reduction in viral plaque at 1.25 uM measured after 6 days by microscopic analysis | Human betaherpesvirus 5 | 2 | ALA4699411 | cell-based format | Scientific Literature | |
7. | ALA4700033 | Toxicity | Selectivity index, ratio of CC50 for human MRC5 cells assessed as reduction in nuclei count measured after 6 days for Hoechst 33342 staining based microscopic analysis to EC50 Human cytomegalovirus infected in MRC5 cells measured after 6 days by microscopic analysis | 8 | ALA4699411 | cell-based format | Scientific Literature | ||
8. | ALA4700034 | Toxicity | Selectivity index, ratio of CC50 for human ARPE-19 cells assessed as reduction in nuclei count measured after 6 days for Hoechst 33342 staining based microscopic analysis to EC50 Human cytomegalovirus infected in ARPE-19 cells measured after 10 days by microscopic analysis | 11 | ALA4699411 | cell-based format | Scientific Literature | ||
9. | ALA4700036 | Functional | Antiviral activity against Human cytomegalovirus harboring ANCHOR infected in ARPE-19 cells assessed as reduction in viral infection measured after 6 days by microscopic analysis relative to control | Human betaherpesvirus 5 | 3 | ALA4699411 | cell-based format | Scientific Literature | |
10. | ALA4700037 | Functional | Antiviral activity against Human cytomegalovirus harboring ANCHOR infected in MRC5 cells assessed as reduction in viral infection at measured after 6 days by microscopic analysis relative to control | Human betaherpesvirus 5 | 3 | ALA4699411 | cell-based format | Scientific Literature |