| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4703737 | Functional | Antiviral activity against SARS COV-1 infected in monkey vero 76 cells assessed as reduction in virus-induced cytopathic effect measured after 66 hrs by neutral red method or cell titer glo-based luminescence assay | Severe acute respiratory syndrome-related coronavirus | 18 | ALA4699574 | organism-based format | Scientific Literature | |
| 2. | ALA4703740 | Binding | Reversible inhibition of SARS coronavirus Urbani 3CL protease(9985 to 10902) using TAMRA-SITSAVLQSGFRKMK(DABCYL)-OH as substrate measured for 10 mins by FRET assay | SARS coronavirus Urbani | 16 | ALA4699574 | assay format | Scientific Literature | |
| 3. | ALA4703741 | ADME | Permeability of compound in human Caco-2 cells | Homo sapiens | 7 | ALA4699574 | cell-based format | Scientific Literature | |
| 4. | ALA4703742 | ADME | Half life in dog at 2 mg/kg, iv | Canis lupus familiaris | 1 | ALA4699574 | organism-based format | Scientific Literature | |
| 5. | ALA4703743 | ADME | Metabolic stability in human liver microsomes assessed as half life | Homo sapiens | 1 | ALA4699574 | microsome format | Scientific Literature | |
| 6. | ALA4703744 | Binding | Inhibition of SARS-CoV-2 3CL protease using DABCYLKTSAVLQ-SGFRKME-EDANS as peptide substrate in presence of PF-00835231 inhibitor incubated for 60 mins by FRET assay | Severe acute respiratory syndrome coronavirus 2 | 1 | ALA4699574 | assay format | Scientific Literature | |
| 7. | ALA4703745 | ADME | Inhibition of human cathepsin B | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 8. | ALA4703746 | ADME | Inhibition of human cathepsin B at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 9. | ALA4703747 | ADME | Inhibition of human cathepsin D | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 10. | ALA4703748 | ADME | Inhibition of human cathepsin D at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 11. | ALA4703749 | ADME | Inhibition of human leukocyte elastase | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 12. | ALA4703750 | ADME | Inhibition of human leukocyte elastase at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 13. | ALA4703751 | ADME | Inhibition of human chymotrypsin | Homo sapiens | 1 | ALA4699574 | assay format | Scientific Literature | |
| 14. | ALA4703752 | ADME | Inhibition of human chymotrypsin at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | assay format | Scientific Literature | |
| 15. | ALA4703753 | ADME | Inhibition of human thrombin | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 16. | ALA4703754 | ADME | Inhibition of human thrombin at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 17. | ALA4703755 | ADME | Inhibition of human pepsin | Homo sapiens | 1 | ALA4699574 | assay format | Scientific Literature | |
| 18. | ALA4703756 | ADME | Inhibition of human pepsin at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | assay format | Scientific Literature | |
| 19. | ALA4703757 | ADME | Inhibition of human Caspase 2 | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature | |
| 20. | ALA4703758 | ADME | Inhibition of human Caspase 2 at 10 uM relative to control | Homo sapiens | 1 | ALA4699574 | single protein format | Scientific Literature |
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