# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4742549 | Binding | Binding affinity to DNA-tagged CDK-12 expressed in HEK293 cells (unknown origin) by qPCR analysis | Homo sapiens | 18 | ALA4742395 | cell-based format | Patent Bioactivity Data | |
2. | ALA4742550 | Binding | Inhibition of CDK12 (unknown origin) using ULight - 4E - BP1( Thr37 / Thr46 ) as substrate preincubated for 60 mins bu LANCE-TR-FRET assay | Homo sapiens | 37 | ALA4742395 | single protein format | Patent Bioactivity Data | |
3. | ALA4742551 | Binding | Binding affinity to CDK13 (unknown origin) by TR-FRET assay | Homo sapiens | 36 | ALA4742395 | single protein format | Patent Bioactivity Data | |
4. | ALA4742552 | Binding | Inhibition of CDK7 (unknown origin) using ULight -mylein basic protein as substrate preincubated for 60 mins bu LANCE-TR-FRET assay | Homo sapiens | 22 | ALA4742395 | single protein format | Patent Bioactivity Data | |
5. | ALA4742553 | Binding | Selectivity index, ratio of IC50 for inhibition of CDK7 (unknown origin) to IC50 for inhibition of CDK12 (unknown origin) | Homo sapiens | 19 | ALA4742395 | assay format | Patent Bioactivity Data | |
6. | ALA4742554 | Binding | Selectivity index, ratio of IC50 for inhibition of CDK7 (unknown origin) to IC50 for binding affinity to CDK13 (unknown origin) | Homo sapiens | 20 | ALA4742395 | assay format | Patent Bioactivity Data | |
7. | ALA4742555 | Binding | Binding affinity to CDK12 in human Jurkat cells assessed as target occupancy after 6 hrs by spectrophotometry | Homo sapiens | 18 | ALA4742395 | cell-based format | Patent Bioactivity Data |