# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4685761 | B | Protac activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation measured after 16 hrs by immunoblotting analysis | Homo sapiens | 5 | ALA4680217 | cell-based format | Scientific Literature | |
2. | ALA4769809 | F | Antiproliferative activity against human MyLa1929 cells assessed as cell viability measured after 72 hrs by MTS assay | Homo sapiens | 20 | ALA4765315 | cell-based format | Scientific Literature | |
3. | ALA4769811 | F | Antiproliferative activity against human MOLT-4 cells assessed as cell viability measured after 72 hrs by MTS assay | Homo sapiens | 3 | ALA4765315 | cell-based format | Scientific Literature | |
4. | ALA4769813 | B | Protac activity at BCL-XL/CRBN in human MyLa1929 cells assessed as degradation of BCL-XL at 0.01 to 3 uM measured after 16 hrs by western blot analysis | Homo sapiens | 1 | ALA4765315 | cell-based format | Scientific Literature | |
5. | ALA5108726 | B | PROTAC activity at CRBN/Bcl-xL in human MOLT-4 cells assessed as induction of Bcl-xL degradation incubated for 16 hrs by Western blot assay | Homo sapiens | 1 | ALA5107957 | cell-based format | Scientific Literature | |
6. | ALA5108727 | B | PROTAC activity at CRBN/Bcl-xL in human MOLT-4 cells assessed as induction of Bcl-xL degradation at 100 nM incubated for 16 hrs by Western blot assay relative to control | Homo sapiens | 1 | ALA5107957 | cell-based format | Scientific Literature | |
7. | ALA5108728 | F | Cytotoxicity against human MOLT-4 cells assessed as cell growth inhibition incubated for 72 hrs | Homo sapiens | 2 | ALA5107957 | cell-based format | Scientific Literature | |
8. | ALA5108729 | T | Cytotoxicity against human platelets assessed as cell growth inhibition incubated for 24 hrs | Homo sapiens | 2 | ALA5107957 | cell-based format | Scientific Literature | |
9. | ALA5108730 | T | Selectivity ratio of IC50 for human platelets to IC50 for human MOLT-4 cells | 1 | ALA5107957 | assay format | Scientific Literature | ||
10. | ALA5215147 | B | PROTAC activity at CRBN/BCL-XL in human MOLT-4 cells assessed as induction of BCL-XL degradation incubated for 16 hrs by Western blot analysis | Homo sapiens | 1 | ALA5214885 | cell-based format | Scientific Literature |