# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4775527 | Binding | Inhibition of TYK2 JH2 domain (unknown origin) by HTRF assay | Homo sapiens | 28 | ALA4765480 | single protein format | Scientific Literature | |
2. | ALA4775528 | Binding | Inhibition of TYK2 in IFN-alpha stimulated human Kit225 T cells by luciferase reporter gene assay | Homo sapiens | 28 | ALA4765480 | tissue-based format | Scientific Literature | |
3. | ALA4775529 | Binding | Inhibition of TYK2 in human whole blood assessed as decrease in IFNalpha-induced STAT5 phosphorylation | Homo sapiens | 28 | ALA4765480 | tissue-based format | Scientific Literature | |
4. | ALA4775530 | ADME | Stability in human liver microsomes assessed as parent compound remaining after 10 mins | Homo sapiens | 7 | ALA4765480 | microsome format | Scientific Literature | |
5. | ALA4775531 | ADME | Stability in rat liver microsomes assessed as parent compound remaining after 10 mins | Rattus norvegicus | 7 | ALA4765480 | microsome format | Scientific Literature | |
6. | ALA4775532 | ADME | Stability in mouse liver microsomes assessed as parent compound remaining after 10 mins | Mus musculus | 7 | ALA4765480 | microsome format | Scientific Literature |