# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4730476 | F | Effect on IP-1 accumulation in CHO-K1 cells over-expressing GNA14 incubated for 90 mins by IP-one assay | Cricetulus griseus | 3 | ALA4725415 | cell-based format | Scientific Literature | |
2. | ALA4730477 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation at 20 uM incubated for 90 mins by IP-one assay relative to basal level | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
3. | ALA4730478 | B | Inhibition of human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as IP-1 accumulation at 50 uM incubated for 90 mins by IP-one assay relative to basal level | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
4. | ALA4730479 | T | Toxicity in human HepG2 cells assessed as reduction in cell viability up to 250 uM incubated for 72 hrs by CellTiter-Glo assay | Homo sapiens | 3 | ALA4725415 | cell-based format | Scientific Literature | |
5. | ALA4730480 | T | Toxicity in human HepG2 cells assessed as cell survival at 62.5 uM incubated for 72 hrs by CellTiter-Glo assay | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
6. | ALA4730481 | T | Toxicity in human HepG2 cells assessed as cell survival at <30 uM incubated for 72 hrs by CellTiter-Glo assay | Homo sapiens | 5 | ALA4725415 | cell-based format | Scientific Literature | |
7. | ALA4730483 | F | Induction of wound closure in human HaCaT cells at 1 uM measured after 48 hrs by light microscopy based wound healing assay relative to control | Homo sapiens | 2 | ALA4725415 | cell-based format | Scientific Literature | |
8. | ALA4730486 | F | Induction of wound closure in human HaCaT cells at 1 uM measured up to 96 hrs by light microscopy based wound healing assay relative to control | Homo sapiens | 2 | ALA4725415 | cell-based format | Scientific Literature | |
9. | ALA4730487 | F | Induction of wound closure in human HaCaT cells at 1 uM by light microscopy based wound healing assay relative to control | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
10. | ALA4730488 | F | Induction of wound closure in human HaCaT cells at 1 uM measured after 24 hrs by light microscopy based wound healing assay relative to control | Homo sapiens | 2 | ALA4725415 | cell-based format | Scientific Literature | |
11. | ALA4730490 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay | Homo sapiens | 51 | ALA4725415 | cell-based format | Scientific Literature | |
12. | ALA4730491 | B | Agonist activity at human BLT2 isoform 2 expressed in CHO-K1 cells over-expressing GNA14 assessed as stimulation of IP-1 accumulation incubated for 90 mins by IP-one assay relative to CAY10583 | Homo sapiens | 40 | ALA4725415 | cell-based format | Scientific Literature | |
13. | ALA4730496 | B | Agonist activity at human BLT1 isoform 1 expressed in CHO-K1 cells over-expressing GNA15/16 assessed as stimulation of IP-1 accumulation at >=20 uM incubated for 90 mins by IP-one assay relative to control | Homo sapiens | 1 | ALA4725415 | cell-based format | Scientific Literature | |
14. | ALA4730497 | P | Solubility of compound in PBS buffer at pH 7.4 containing 1% dimethyl sulfoxide | 3 | ALA4725415 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA4730498 | A | Metabolic stability in Sprague-Dawley rat liver microsomes assessed as parent compound remaining at 1 mM in presence of NADPH measured after 60 mins by HPLC analysis | Rattus norvegicus | 3 | ALA4725415 | microsome format | Scientific Literature |