# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4770665 | Binding | Substrate activity at recombinant human C-terminal His-tagged NQO1 (1 to 274 residues) expressed in Escherichia coli assessed as enzyme activity by measuring oxidation of NADPH incubated for 5 mins measured per micromol of enzyme every 5 sec for 1 mins by UV-visible spectrophotometry | Homo sapiens | 31 | ALA4765339 | assay format | Scientific Literature | |
2. | ALA4770667 | Functional | Cytotoxicity against NQO1-rich human MCF7 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4765339 | cell-based format | Scientific Literature | |
3. | ALA4770668 | Functional | Cytotoxicity against human HepG2 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4765339 | cell-based format | Scientific Literature | |
4. | ALA4770669 | Functional | Cytotoxicity against human A549 cells assessed as reduction in cell growth incubated for 48 hrs by MTT assay | Homo sapiens | 7 | ALA4765339 | cell-based format | Scientific Literature |