| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA4775686 | B | Binding affinity to biotinylated human TNFalpha trimer (77 to 233 residues) expressed in Escherichia coli BL21(DE3) by SPR analysis | Homo sapiens | 11 | ALA4765484 | assay format | Scientific Literature | |
| 2. | ALA4775687 | B | Binding affinity to biotinylated human TNFalpha trimer (77 to 233 residues) expressed in Escherichia coli BL21(DE3) assessed as binding constant (Kon) by SPR analysis | Homo sapiens | 11 | ALA4765484 | assay format | Scientific Literature | |
| 3. | ALA4775688 | B | Binding affinity to biotinylated human TNFalpha trimer (77 to 233 residues) expressed in Escherichia coli BL21(DE3) assessed as binding constant (Koff) by SPR analysis | Homo sapiens | 11 | ALA4765484 | assay format | Scientific Literature | |
| 4. | ALA4775689 | B | Induction of stabilization of biotinylated human TNFalpha trimer (77 to 233 residues) expressed in Escherichia coli BL21(DE3) assessed as change in melting temperature | Homo sapiens | 3 | ALA4765484 | assay format | Scientific Literature | |
| 5. | ALA4775692 | B | Inhibition of probe-5 binding to human TNFalpha (77 to 233 residues) at 1 nM by fluorescence polarization assay | Homo sapiens | 11 | ALA4765484 | single protein format | Scientific Literature | |
| 6. | ALA4775698 | B | Inhibition of TNFalpha in mouse L929 cells exposed to compound incubated for 1 hr with mouse TNFalpha by luminescence based assay | Mus musculus | 11 | ALA4765484 | cell-based format | Scientific Literature |
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