# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4768557 | ADME | Cytotoxicity against human Platelet assessed as increase in LDH leakage at 200 uM after 10 mins by LDH assay | Homo sapiens | 14 | ALA4765278 | cell-based format | Scientific Literature | |
2. | ALA4768558 | Functional | Inhibition of collagen-induced platelet aggregation in human platelet preincubated for 5 mins followed by collagen-stimulation and measured after 6 mins by lumi-aggregometric method | Homo sapiens | 12 | ALA4765278 | tissue-based format | Scientific Literature | |
3. | ALA4768559 | Functional | Inhibition of TRAP6-induced platelet aggregation in human platelet preincubated for 5 mins followed by TRAP6-stimulation and measured after 6 mins by lumi-aggregometric method | Homo sapiens | 12 | ALA4765278 | tissue-based format | Scientific Literature | |
4. | ALA4768560 | Functional | Selectivity index, ratio of IC50 for inhibition of TRAP6-induced platelet aggregation in human platelet to IC50 for inhibition of collagen-induced platelet aggregation in human platelet | Homo sapiens | 12 | ALA4765278 | tissue-based format | Scientific Literature |