# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4678670 | F | In vivo inhibition of ACSL1 in mouse assessed as reduction in acyl-coA production in liver administered orally using palmitoleic acid as substrate and measured after 17 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA4678671 | F | In vivo inhibition of ACSL1 in mouse assessed as reduction in acyl-coA production in liver administered orally using oleic acid as substrate and measured after 17 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
3. | ALA4678672 | F | In vivo inhibition of ACSL1 in mouse assessed as reduction in acyl-coA production in liver administered orally using palmitic acid as substrate and measured after 17 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
4. | ALA4678673 | A | Tmax in rat at 1 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
5. | ALA4678674 | A | Cmax in rat at 1 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA4678675 | A | Oral bioavailability in rat at 1 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
7. | ALA4678676 | A | AUC in rat at 1 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
8. | ALA4678677 | A | Half life in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
9. | ALA4678678 | A | Volume of distribution at steady state in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
10. | ALA4678679 | A | Total clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
11. | ALA4678680 | A | AUC in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
12. | ALA4678681 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
13. | ALA4678682 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
14. | ALA4678683 | A | Fraction unbound in rat plasma | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
15. | ALA4678684 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
16. | ALA4678685 | A | Inhibition of CYP2C9 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA4678686 | P | Solubility of compound in pH 6.8 with TCA | 1 | small-molecule physicochemical format | Scientific Literature | |||
18. | ALA4678687 | A | Inhibition of CYP1A2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA4678688 | P | Solubility of compound in pH 1.2 | 1 | small-molecule physicochemical format | Scientific Literature | |||
20. | ALA4678689 | P | Solubility of compound in pH 6.8 | 1 | small-molecule physicochemical format | Scientific Literature |