# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4703703 | B | Modulation of recombinant human FGF141b (1 to 252 residues)-recombinant human Nav1.6 C-terminal tail (1763 to 1976 residues) protein-protein interaction expressed in HEK293 cells assessed as relative luminescence value at 50 uM measured at 2 mins interval for 20 mins by split-luciferase complementation assay relative to control | Homo sapiens | 33 | cell-based format | Scientific Literature | ||
2. | ALA4703704 | B | Modulation of recombinant human FGF141b (1 to 252 residues)-recombinant human Nav1.6 C-terminal tail (1763 to 1976 residues) protein-protein interaction expressed in HEK293 cells measured at 2 mins interval for 20 mins by split-luciferase complementation assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
3. | ALA4703705 | B | Modulation of recombinant human FGF141b (1 to 252 residues)-recombinant human Nav1.6 C-terminal tail (1763 to 1976 residues) protein-protein interaction expressed in HEK293 cells measured at 2 mins interval for 20 mins by split-luciferase complementation assay relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
4. | ALA4703706 | B | Inhibition of full-length Photinus pyralis luciferase transfected in HEK293 cells at 25 uM incubated for 1 hrs by split-luciferase complementation assay | Photinus pyralis | 12 | cell-based format | Scientific Literature | ||
5. | ALA4703707 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability measured after 20 mins by celltiter-blue assay | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
6. | ALA4703708 | B | Binding affinity to human recombinant FGF14 expressed in Escherichia coli BL21 assessed as assessed as induction of protein denaturation by measuring change in melting temperature at 50 uM by fluorescent dye based thermal shift assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
7. | ALA4703709 | B | Binding affinity to human recombinant Nav1.6 C-terminal domain expressed in Escherichia coli BL21 assessed as assessed as induction of protein denaturation by measuring change in melting temperature at 10 uM by fluorescent dye based thermal shift assay | Homo sapiens | 7 | assay format | Scientific Literature | ||
8. | ALA4703710 | B | Binding affinity to human recombinant FGF14 expressed in Escherichia coli BL21 assessed as dissociation constant by SPR analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
9. | ALA4703711 | B | Binding affinity to human recombinant Nav1.6 C-terminal domain expressed in Escherichia coli BL21 assessed as dissociation constant by SPR analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
10. | ALA4703712 | B | Binding affinity to human recombinant FGF14 expressed in Escherichia coli BL21 assessed as association rate constant by SPR analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
11. | ALA4703713 | B | Binding affinity to human recombinant FGF14 expressed in Escherichia coli BL21 assessed as dissociation rate constant by SPR analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
12. | ALA4703714 | B | Binding affinity to human recombinant Nav1.6 C-terminal domain expressed in Escherichia coli BL21 assessed as association rate constant by SPR analysis | Homo sapiens | 9 | assay format | Scientific Literature | ||
13. | ALA4703715 | B | Binding affinity to human recombinant Nav1.6 C-terminal domain expressed in Escherichia coli BL21 assessed as dissociation rate constant by SPR analysis | Homo sapiens | 9 | assay format | Scientific Literature |