# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA4775730 | Binding | Binding affinity to VDR (unknown origin) at 1 uM by fluorescence polarization assay relative to calcipotriol | Homo sapiens | 57 | ALA4765486 | single protein format | Scientific Literature | |
2. | ALA4775731 | ADME | Cytotoxicity against rat LTC-14 cells assessed as reduction in cell proliferation incubated for 24 hrs by MTT assay | Rattus norvegicus | 58 | ALA4765486 | cell-based format | Scientific Literature | |
3. | ALA4775732 | Functional | Inhibition of rat LTC-14 cell activation assessed decrease in TGF-beta1 induced Colla1 mRNA expression at 0.5 uM incubated for 24 hrs by q-PCR analysis | Rattus norvegicus | 58 | ALA4765486 | tissue-based format | Scientific Literature | |
4. | ALA4775733 | Functional | Inhibition of rat LTC-14 cells activation assessed decrease in TGF-beta1 induced Acta2 mRNA expression at 0.5 uM incubated for 24 hrs by q-PCR analysis | Rattus norvegicus | 58 | ALA4765486 | tissue-based format | Scientific Literature | |
5. | ALA4775734 | Functional | Inhibition of rat LTC-14 cells activation assessed decrease in TGF-beta1 induced collagen 1 protein expression at 0.5 uM incubated for 24 hrs by Western blot analysis | Rattus norvegicus | 58 | ALA4765486 | tissue-based format | Scientific Literature |